Use of a Caco-2 permeability assay to evaluate the effects of several Kampo medicines on the drug transporter P-glycoprotein
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Natural Medicines"
DOI: 10.1007/s11418-018-1222-x
Abstract: In modern medical care in which Kampo and Western drugs are often combined, it is extremely important to clarify drug–drug interaction (DDI) to ensure safety and efficacy. However, there is little evidence of DDI in… read more here.
Keywords: five kampo; kampo medicines; drug; transporter glycoprotein ... See more keywords
A Japanese traditional medicine Hochuekkito promotes negative conversion of vancomycin-resistant Enterococci
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-90890-4
Abstract: Vancomycin-resistant enterococci (VRE) are prominent causes of nosocomial infections. Japanese traditional (Kampo) medicine promotes intestinal immunity and protects against bacterial infections. We assessed potential differences in the clinical course of VRE-positive patients, based on their… read more here.
Keywords: medicine; vre negative; negative conversion; kampo medicines ... See more keywords
Identifying Crude Drugs in Kampo Medicines Associated with Drug-Induced Liver Injury Using the Japanese Adverse Drug Event Report Database: A Comprehensive Survey
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16050678
Abstract: The current study aimed to identify the crude drugs associated with drug-induced liver injury (DILI) in 148 Kampo medicines prescribed throughout Japan using the Japanese Adverse Drug Event Report (JADER) database, a large-scale spontaneous reporting… read more here.
Keywords: crude drugs; kampo medicines; event; adverse drug ... See more keywords