Systematic analysis of Kaposi's sarcoma (KS)‐associated herpesvirus genomes from a KS case‐control study in Cameroon: Evidence of dual infections but no association between viral sequence variation and KS risk
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DOI: 10.1002/ijc.34136
Abstract: In sub‐Saharan Africa, Kaposi's sarcoma‐associated herpesvirus (KSHV) is endemic, and Kaposi's sarcoma (KS) is a significant public health problem. Until recently, KSHV genotype analysis was performed using variable gene regions, representing a small fraction of… read more here.
Keywords: control; sequence; kaposi sarcoma; analysis ... See more keywords
Kaposi sarcoma‐associated herpesvirus, HIV‐1 and Kaposi sarcoma risk in black South Africans diagnosed with cancer during antiretroviral treatment rollout
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DOI: 10.1002/ijc.34454
Abstract: Kaposi sarcoma‐associated herpesvirus (KSHV) causes Kaposi sarcoma (KS). The risk of KS is amplified in HIV‐immunosuppressed individuals and antiretroviral therapy (ART) reduces KS incidence. Reliable data on the relationship between these factors are lacking in… read more here.
Keywords: rollout; kaposi sarcoma; hiv; art rollout ... See more keywords
Enhanced phosphorylation of sphingosine and ceramide sustains the exuberant proliferation of endothelial progenitors in Kaposi sarcoma
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DOI: 10.1002/jlb.2ma0817-312r
Abstract: Endothelial colony‐forming cells (ECFCs), a unique endothelial stem cell population, are highly increased in the blood of Kaposi sarcoma (KS) patients. KS‐derived ECFCs (KS‐ECFCs) are also endowed with increased proliferative and vasculogenic potential, thus suggesting… read more here.
Keywords: kaposi sarcoma; proliferation; sphingosine; s1p ... See more keywords
Social behavioral correlates of Kaposi sarcoma–associated herpesvirus infection among Han and Uygur populations in Xinjiang, China
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DOI: 10.1002/jmv.25332
Abstract: Kaposi sarcoma–associated herpesvirus (KSHV) is endemic in Xinjiang, China and its prevalence varies considerably across ethnic groups. The current study explored the prevalence and correlates of KSHV infection among Han and Uygur populations in Xinjiang. read more here.
Keywords: kaposi sarcoma; infection among; among han; xinjiang china ... See more keywords
Human leukocyte antigen polymorphisms and Kaposi's sarcoma‐associated herpesvirus infection outcomes: A call for deeper exploration
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DOI: 10.1002/jmv.25342
Abstract: Host genetic background may influence the immunity to resist viral infection. As the most polymorphic loci in the entire human genome, the human leukocyte antigen (HLA) system plays an important role in innate and adaptive… read more here.
Keywords: kaposi sarcoma; infection; human leukocyte; associated herpesvirus ... See more keywords
CXCL1 confers a survival advantage in Kaposi's sarcoma‐associated herpesvirus‐infected human endothelial cells through STAT3 phosphorylation
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DOI: 10.1002/jmv.28020
Abstract: Many cytokines produced by Kaposi's sarcoma‐associated herpesvirus (KSHV)‐infected cells have been shown to participate in the pathogenesis of KSHV. Determination of the exact role of cytokines in Kaposi's sarcoma (KS) pathogenesis is limited, however, by… read more here.
Keywords: kshv infected; cxcl1; endothelial cells; kshv ... See more keywords
An endothelial cell line infected by Kaposi’s sarcoma–associated herpes virus (KSHV) allows the investigation of Kaposi’s sarcoma and the validation of novel viral inhibitors in vitro and in vivo
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DOI: 10.1007/s00109-018-01733-1
Abstract: Kaposi’s sarcoma–associated herpesvirus (KSHV) is the etiological agent of Kaposi’s sarcoma (KS), a tumor of endothelial origin predominantly affecting immunosuppressed individuals. Up to date, vaccines and targeted therapies are not available. Screening and identification of… read more here.
Keywords: cell line; kaposi sarcoma; kshv; endothelial cell ... See more keywords
Colorectal Kaposi Sarcoma in an Immunosuppressed Ulcerative Colitis Patient
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DOI: 10.1007/s11605-017-3649-x
Abstract: A 49-year-old man with a long history of left-sided ulcerative colitis (UC), treated primarily with mesalamine and intermittent steroid enemas, developed recurrent flares associated with worsening bloody diarrhea. This resulted in the need for repeated… read more here.
Keywords: kaposi sarcoma; sarcoma immunosuppressed; colitis; ulcerative colitis ... See more keywords
Lipids, lipid metabolism and Kaposi’s sarcoma-associated herpesvirus pathogenesis
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DOI: 10.1007/s12250-017-4027-2
Abstract: AbstractLipids are essential for mammalian cells to maintain many physiological functions. Emerging evidence has shown that cancer cells can develop specific alterations in lipid biosynthesis and metabolism to facilitate their survival and various malignant behaviors.… read more here.
Keywords: lipids lipid; metabolism; kaposi sarcoma; pathogenesis ... See more keywords
Kaposi’s sarcoma: a single-center experience on 38 patients
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DOI: 10.1016/j.abd.2021.02.007
Abstract: aposi’s Sarcoma (KS) is a multifocal angioproliferative neolasm associated with infection by Human Herpes Virus type (HHV8).1,2 We retrospectively studied 38 biopsy-proven KS diagosed at our department between 2010 and 2019. The patients’ mean age… read more here.
Keywords: single center; experience patients; kaposi sarcoma; center experience ... See more keywords
Aggressive conjunctival Kaposi sarcoma as the initial manifestation of acquired immunodeficiency syndrome
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DOI: 10.1016/j.ajoc.2020.100832
Abstract: Purpose To report a case of Kaposi sarcoma in a patient with previously undiagnosed Human Immunodeficiency Virus (HIV) infection. Observations A 23-year-old male patient presented to the eye clinic with complaints of redness of his… read more here.
Keywords: conjunctival kaposi; kaposi sarcoma; hiv; mass ... See more keywords