Splenic kaposiform hemangioendothelioma presenting as insidious consumptive coagulopathy
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Hematology"
DOI: 10.1002/ajh.26370
Abstract: A healthy 2-year-old male with a history of mild persistent asthma visited the outpatient hematology clinic to evaluate intermittent epistaxis. There was no history of recent illness. His exam was notable for left upper extremity… read more here.
Keywords: kaposiform hemangioendothelioma; hematology; blood; marrow ... See more keywords
Sirolimus Treatment of an Infant With Intrathoracic Kaposiform Hemangioendothelioma Complicated by Life-threatening Pleural and Pericardial Effusions.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000001268
Abstract: Kaposiform hemangioendothelioma (KHE) is a rare infiltrative vascular tumor that may be associated with Kasabach-Merritt Phenomenon (KMP), which is a consumptive coagulopathy with potentially life-threatening thrombocytopenia. Management of KHE and KMP is challenging, and currently,… read more here.
Keywords: threatening pleural; treatment; life threatening; pleural pericardial ... See more keywords
First Intracardiac Kaposiform Hemangioendothelioma in an Infant Resolved With Sirolimus: A Case Report
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000001275
Abstract: Introduction: Kaposiform hemangioendothelioma (KHE) is a rare and aggressive vascular tumor that can be associated with a consumptive coagulopathy and thrombocytopenia (Kasabach-Merritt phenomenon). Only one case of an intracardiac KHE has been reported which was… read more here.
Keywords: first intracardiac; intracardiac kaposiform; kaposiform hemangioendothelioma; case ... See more keywords
18F-FDG PET/CT Findings in a Woman With Kaposiform Hemangioendothelioma in the Sacrum.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000004000
Abstract: ABSTRACT Kaposiform hemangioendothelioma is a rare vascular tumor with borderline malignancy and is typically diagnosed in infancy or early childhood. It most commonly affects cutaneous tissues, whereas the subtype with only primary bone involvement is… read more here.
Keywords: 18f fdg; kaposiform hemangioendothelioma; woman; fdg pet ... See more keywords
Sirolimus for Kaposiform Hemangioendothelioma With Kasabach-Merritt Phenomenon in Two Infants.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Craniofacial Surgery"
DOI: 10.1097/scs.0000000000006301
Abstract: Kaposiform hemangioendothelioma is an aggressive vascular tumor with infiltrative growth that commonly occurs in infancy and is associated with a life-threatening consumptive coagulopathy, as well as Kasabach-Merritt phenomenon. Recently, promising results have shown that sirolimus… read more here.
Keywords: kasabach merritt; merritt phenomenon; kaposiform hemangioendothelioma;
The use of mTOR inhibitors for the treatment of kaposiform hemangioendothelioma. A systematic review
Sign Up to like & getrecommendations! Published in 2023 at "Pediatric Dermatology"
DOI: 10.1111/pde.15262
Abstract: Kaposiform hemangioendothelioma (KHE) is a locally aggressive and potentially lethal vascular tumor of infancy. Current consensus recommendations include the use of vincristine and/or systemic steroids as first‐line treatment. Mammalian target of rapamycin (mTOR) inhibitors represent… read more here.
Keywords: mtor; kaposiform hemangioendothelioma; treatment; mtor inhibitors ... See more keywords
Kaposiform Hemangioendothelioma: clinicopathological characteristics of 8 cases of a rare vascular tumor and review of literature
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostic Pathology"
DOI: 10.1186/s13000-021-01080-9
Abstract: Background Kaposiform Hemangioendothelioma (KHE) is a rare vascular tumor of intermediate malignant potential which shows locally aggressive growth but only rarely metastasizes. It is mostly considered to be a tumor of pediatric population but its… read more here.
Keywords: tumor; pathology; hemangioendothelioma clinicopathological; vascular tumor ... See more keywords
Pneumocystis Jirovecii Pneumonia During Sirolimus Therapy for Kaposiform Hemangioendothelioma
Sign Up to like & getrecommendations! Published in 2018 at "Pediatrics"
DOI: 10.1542/peds.2017-1044
Abstract: An infant with KHE with KMP developed PCP while on sirolimus. Pneumocystis prophylaxis should be considered for patients receiving sirolimus. Sirolimus is an effective therapy for children with kaposiform hemangioendothelioma with or without the Kasabach-Merritt… read more here.
Keywords: pneumocystis; sirolimus; kaposiform hemangioendothelioma; sirolimus therapy ... See more keywords
Multifocal Kaposiform Hemangioendothelioma in a Newborn With Confirmatory Histopathology.
Sign Up to like & getrecommendations! Published in 2022 at "Pediatrics"
DOI: 10.1542/peds.2022-056293
Abstract: Kaposiform hemangioendothelioma is classified as a locally aggressive vascular tumor of childhood resulting from abnormal angiogenesis and lymphangiogenesis. Most commonly, KHE presents as a single tissue mass, ranging from an erythematous papule to a violaceous… read more here.
Keywords: multifocal kaposiform; kaposiform hemangioendothelioma; histopathology; hemangioendothelioma newborn ... See more keywords
Case Report: Pancreatic and hepatic kaposiform hemangioendothelioma presenting as consumptive coagulopathy and right hepatic atrophy
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1097997
Abstract: Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor that causes progressive angiogenesis and lymphangiogenesis, which often occurs in the skin or soft tissue, with an acute onset and rapid progression. A 4-year-old girl was admitted… read more here.
Keywords: hepatic atrophy; kaposiform hemangioendothelioma; right hepatic;
Case Report: Kaposiform hemangioendothelioma with PIK3CA mutation successfully treated with sirolimus
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1132702
Abstract: Kaposiform hemangioendothelioma (KHE) is an extremely rare, locally aggressive vascular neoplasm. The etiopathogenesis of KHE is still poorly understood. In the present study, we found a new mutation in KHE (c.685delA, p.Thr229fs). The KHE patient… read more here.
Keywords: hemangioendothelioma pik3ca; pik3ca mutation; case report; mutation ... See more keywords