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Extracellular CIRP Upregulates Proinflammatory Cytokine Expression via the NF-kappaB and ERK1/2 Signaling Pathways in Psoriatic Keratinocytes

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Published in 2022 at "Mediators of Inflammation"

DOI: 10.1155/2022/5978271

Abstract: Psoriasis is a chronic inflammatory skin disease, and elevation of proinflammatory cytokine levels is a critical driver of the pathogenesis of psoriasis. Extracellular cold-inducible RNA-binding protein (eCIRP) has been shown to play a role in… read more here.

Keywords: proinflammatory cytokine; kappab erk1; psoriatic keratinocytes; expression ... See more keywords