The angiotensin-converting enzyme inhibitor, captopril, suppressed Hepatic Stellate Cell activation via NF-kappaB or wnt3α/β-catenin pathway.
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DOI: 10.1080/21655979.2021.1987091
Abstract: Activation of hepatic stellate cells (HSC) is associated with hepatic fibrogenesis, which is one of complications of diabetes mellitus. Captopril possesses potent anti-inflammation, oxidative stress and fibrosis effects. However, the specific molecular mechanism of captopril… read more here.
Keywords: wnt3 catenin; kappab wnt3; captopril; cell ... See more keywords