Effects of Kasugamycin on the Translatome of Escherichia coli
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DOI: 10.1371/journal.pone.0168143
Abstract: It is long known that Kasugamycin inhibits translation of canonical transcripts containing a 5’-UTR with a Shine Dalgarno (SD) motif, but not that of leaderless transcripts. To gain a global overview of the influence of… read more here.
Keywords: translatome escherichia; escherichia coli; resistance; kasugamycin ... See more keywords
KasQ an Epimerase Primes the Biosynthesis of Aminoglycoside Antibiotic Kasugamycin and KasF/H Acetyltransferases Inactivate Its Activity
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DOI: 10.3390/biomedicines10020212
Abstract: Kasugamycin (KSM), an aminoglycoside antibiotic, is composed of three chemical moieties: D-chiro-inositol, kasugamine and glycine imine. Despite being discovered more than 50 years ago, the biosynthetic pathway of KSM remains an unresolved puzzle. Here we… read more here.
Keywords: epimerase primes; kasq epimerase; kasugamycin; aminoglycoside antibiotic ... See more keywords