New ent-kaurane diterpenes with chiral epoxyangelate moieties from Wedelia prostrata
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DOI: 10.1016/j.cclet.2018.05.038
Abstract: Abstract Four new ent-kaurane diterpenes with chiral epoxyangelate moieties, (2′R,3′R)-3α-(2′,3′-epoxyangeloyloxy)-kaur-16-en-19-oic acid (1), (2′S,3′S)-3α-(2′,3′-epoxyangeloyloxy)-kaur-16-en-19-oic acid (2), (2′S,3′R)-3α-(2′,3′-epoxyangeloyloxy)-kaur-16-en-19-oic acid (3) and (2′R,3′S)-3α-(2′,3′-epoxyangeloyloxy)-kaur-16-en-19-oic acid (4), along with eight known diterpenes (5−12), were isolated from Wedelia prostrata. The absolute… read more here.
Keywords: chiral epoxyangelate; epoxyangelate moieties; new ent; kaurane diterpenes ... See more keywords
Bioactive Ent-Kaurane Diterpenes Oridonin and Irudonin Prevent Cancer Cells Migration by Interacting with the Actin Cytoskeleton Controller Ezrin
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DOI: 10.3390/ijms21197186
Abstract: The ent-kaurane diterpene oridonin was reported to inhibit cell migration and invasion in several experimental models. However, the process by which this molecule exerts its anti-metastatic action has not been yet elucidated. In this article,… read more here.
Keywords: cytoskeleton; ent kaurane; migration; cancer ... See more keywords