Identification of Kazal Inhibitor Scaffolds with Identical Canonical Binding Loops and Their Effects on Binding Properties
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DOI: 10.1021/acs.biochem.2c00573
Abstract: Kazal inhibitors hold high potential as scaffolds for therapeutic molecules, taking advantage of the easily exchangeable canonical binding loop. Different Kazal inhibitor backbones have been suggested to be therapeutically useful, but the impact of different… read more here.
Keywords: kazal inhibitor; canonical binding; binding properties; inhibitor ... See more keywords