Articles with "kca" as a keyword



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Effects of KCa channels on biological behavior of trophoblasts

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Published in 2022 at "Open Life Sciences"

DOI: 10.1515/biol-2022-0462

Abstract: Abstract The Ca2+-activated potassium (KCa) channels are involved in many cellular functions, but their roles in trophoblasts are unclear. This study aimed to clarify the effects of KCa channels on the biological behavior of trophoblasts.… read more here.

Keywords: effects kca; behavior trophoblasts; channels biological; kca ... See more keywords
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The Trials and Tribulations of Structure Assisted Design of KCa Channel Activators

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Published in 2019 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2019.00972

Abstract: Calcium-activated K+ channels constitute attractive targets for the treatment of neurological and cardiovascular diseases. To explain why certain 2-aminobenzothiazole/oxazole-type KCa activators (SKAs) are KCa3.1 selective we previously generated homology models of the C-terminal calmodulin-binding domain… read more here.

Keywords: cam; kca channel; channel activators; structure ... See more keywords