Activation of 5-HT2A Receptors Restores KCC2 Function and Reduces Neuropathic Pain after Spinal Cord Injury
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DOI: 10.1016/j.neuroscience.2017.08.033
Abstract: Downregulation of the potassium chloride cotransporter type 2 (KCC2) after a spinal cord injury (SCI) disinhibits motoneurons and dorsal horn interneurons causing spasticity and neuropathic pain, respectively. We showed recently (Bos et al., 2013) that… read more here.
Keywords: ht2a receptors; kcc2 function; neuropathic pain; injury ... See more keywords