Discovery of Small Molecule KCC2 Potentiators Which Attenuate In Vitro Seizure-Like Activity in Cultured Neurons
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DOI: 10.3389/fcell.2022.912812
Abstract: KCC2 is a K+-Cl− cotransporter that is expressed in neurons throughout the central nervous system. Deficits in KCC2 activity have been implicated in a variety of neurological disorders, including epilepsy, chronic pain, autism spectrum disorders,… read more here.
Keywords: small molecule; kcc2 potentiation; kcc2 potentiators; molecule kcc2 ... See more keywords