Etomidate-Induced myoclonus in Sprague‒Dawley rats involves the activation of neocortical Calpain-2 and its decrement on KCC2 protein
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DOI: 10.1186/s12871-025-03065-3
Abstract: Etomidate-induced myoclonus has become a pressing clinical problem with an incidence of 50–80%. The underlying mechanism involves neocortical glutamate accumulation and N-methyl-d-aspartate (NMDA) receptor activity. However, the therapeutic target remains uncertain. Adult male Sprague-Dawley (SD)… read more here.
Keywords: kcc2 protein; induced myoclonus; etomidate; etomidate induced ... See more keywords