KCC2 Regulates Neuronal Excitability and Hippocampal Activity via Interaction with Task-3 Channels.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.06.001
Abstract: KCC2 regulates neuronal transmembrane chloride gradients and thereby controls GABA signaling in the brain. KCC2 downregulation is observed in numerous neurological and psychiatric disorders. Paradoxical, excitatory GABA signaling is usually assumed to contribute to abnormal… read more here.
Keywords: regulates neuronal; neuronal excitability; kcc2 regulates; downregulation ... See more keywords