KChIP2 Serves Multiple Functions in Cardiac Myocytes in Splice Isoform-Dependent Manner
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DOI: 10.1016/j.bpj.2016.11.230
Abstract: K-channel-interacting-proteins (KChIPs) are EF-hand-motif-bearing Ca sensors that serve diverse functions. KChIP2 is the major KChIP expressed in the heart, that can modulate key cardiac channels (Itof, Nav, CaV and IKur) by directly interacting with their… read more here.
Keywords: kchip2 serves; palmitoylation; kchip2c; kchip2a ... See more keywords
Circadian rhythm in QT interval is preserved in mice deficient of potassium channel interacting protein 2
Sign Up to like & getrecommendations! Published in 2017 at "Chronobiology International"
DOI: 10.1080/07420528.2016.1225074
Abstract: ABSTRACT Potassium Channel Interacting Protein 2 (KChIP2) is suggested to be responsible for the circadian rhythm in repolarization duration, ventricular arrhythmias, and sudden cardiac death. We investigated the hypothesis that there is no circadian rhythm… read more here.
Keywords: rhythm; channel interacting; potassium channel; circadian rhythm ... See more keywords
Modulation of KV4.3-KChIP2 Channels by IQM-266: Role of DPP6 and KCNE2
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DOI: 10.3390/ijms23169170
Abstract: The transient outward potassium current (Itof) is generated by the activation of KV4 channels assembled with KChIP2 and other accessory subunits (DPP6 and KCNE2). To test the hypothesis that these subunits modify the channel pharmacology,… read more here.
Keywords: iqm 266; kcne2; dpp6; kchip2 ... See more keywords