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Published in 2022 at "Physiological genomics"
DOI: 10.1152/physiolgenomics.00134.2021
Abstract: Ion channels are potentially exploitable as pharmacological targets to treat asthma. This study evaluated the role of KCa3.1 channels, encoded by Kcnn4, in regulating the gene expression of mouse airway epithelium and the development of…
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Keywords:
asthma;
trachea bronchi;
expression;
gene expression ... See more keywords
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Published in 2020 at "JCI Insight"
DOI: 10.1172/jci.insight.140076
Abstract: Airway mucociliary clearance (MCC) is the main mechanism of lung defense keeping airways free of infection and mucus obstruction. Airway surface liquid volume, ciliary beating, and mucus are central for proper MCC and critically regulated…
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Keywords:
absorption;
kcnn4;
obstructive lung;
muco obstructive ... See more keywords