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   Articles with "kcnq1ot1" as a keyword



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Long noncoding RNA KCNQ1OT1 promotes proliferation, migration, and invasion in maxillary sinus squamous cell carcinoma by regulating miR‐204/EphA7 axis

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recommendations! Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.29548

Abstract: Long noncoding RNAs have been demonstrated to contribute to the development and progression of various cancers. However, the underlying regulatory mechanisms of KCNQ1OT1 in tumorigenesis of maxillary sinus squamous cell carcinoma (MSSCC) remain unknown. Herein,… read more here.

Keywords: maxillary sinus; long noncoding; sinus squamous; kcnq1ot1 ... See more keywords
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KCNQ1OT1 inhibition alleviates high glucose-induced podocyte injury by adsorbing miR-23b-3p and regulating Sema3A

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recommendations! Published in 2022 at "Clinical and Experimental Nephrology"

DOI: 10.1007/s10157-021-02173-x

Abstract: Diabetic nephropathy (DN), a diabetic complication, is the leading cause of end-stage renal disease. KCNQ1 opposite strand/antisense transcript 1 (KCNQ1OT1), a long non-coding RNA, has been unmasked to participate in the pathogenesis of DN. However,… read more here.

Keywords: apoptosis; mir 23b; proliferation; high glucose ... See more keywords
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LncRNA KCNQ1OT1 acts as miR-216b-5p sponge to promote colorectal cancer progression via up-regulating ZNF146

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recommendations! Published in 2021 at "Journal of Molecular Histology"

DOI: 10.1007/s10735-020-09942-0

Abstract: Long non-coding RNAs (lncRNAs) have shown to act as important regulators in cancer biology. The aim of this study was to investigate the role and mechanism of lncRNA KCNQ1 opposite strand/antisense transcript 1 (KCNQ1OT1) in… read more here.

Keywords: crc cells; mir 216b; znf146; kcnq1ot1 ... See more keywords
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LncRNA KCNQ1OT1 contributes to the progression and chemoresistance in acute myeloid leukemia by modulating Tspan3 through suppressing miR-193a-3p.

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recommendations! Published in 2019 at "Life sciences"

DOI: 10.1016/j.lfs.2019.117161

Abstract: AIMS Acute myeloid leukemia (AML) is an aggressive cancer that invariably produces drug resistance after treatment. The aim is to explore the role of lncRNA potassium voltage-gated channel subfamily Q member 1 overlapping transcript 1… read more here.

Keywords: progression chemoresistance; adr; mir 193a; kcnq1ot1 ... See more keywords
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LncRNA KCNQ1OT1 promotes apoptosis and oxidative stress of human lens epithelial cells through epigenetic regulation of WRN.

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recommendations! Published in 2022 at "Current eye research"

DOI: 10.1080/02713683.2022.2026975

Abstract: PURPOSE Long non-coding RNA KCNQ1OT1 is fundamental to age-related cataract (ARC), whereas the underlying mechanism is still unknown. Here, we explored the possible mechanism of KCNQ1OT1 in ARC. METHODS The expression of KCNQ1OT1 in ARC… read more here.

Keywords: wrn; apoptosis oxidative; sra01 cells; oxidative stress ... See more keywords
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Long non-coding RNA KCNQ1OT1 overexpression promotes osteogenic differentiation of staphylococcus aureus-infected human bone mesenchymal stem cells by sponging microRNA miR-29b-3p

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2037898

Abstract: ABSTRACT Osteomyelitis (OM) is an orthopedic disease caused by bone infections in the bone cortex, bone marrow, periosteum, and surrounding soft tissues. Recent studies have implicated non-coding RNAs (ncRNAs) in the development of OM. However,… read more here.

Keywords: mir 29b; bone; infection; osteogenic differentiation ... See more keywords
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Silencing of LncRNA KCNQ1OT1 confers an inhibitory effect on renal fibrosis through repressing miR-124-3p activity

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2056816

Abstract: ABSTRACT LncRNA have been increasingly shown that plays pivotal roles in the development of various diseases, including renal fibrosis. Nevertheless, the pathological function of Long non-coding RNA KCNQ1OT1 (KCNQ1OT1) in the renal fibrosis remains obscure.… read more here.

Keywords: effect; mir 124; renal fibrosis; tgf induced ... See more keywords
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lncRNA KCNQ1OT1 Promotes EMT, Angiogenesis, and Stemness of Pituitary Adenoma by Upregulation of RAB11A

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recommendations! Published in 2022 at "Journal of Oncology"

DOI: 10.1155/2022/4474476

Abstract: This study is aimed at investigating the effect and mechanism of long noncoding RNA (lncRNA) KCNQ1OT1 on pituitary adenoma (PA). The KCNQ1OT1 expression in invasive and noninvasive PA tissues was detected by real-time fluorescence quantitative… read more here.

Keywords: pituitary adenoma; mir 140; effect; lncrna kcnq1ot1 ... See more keywords
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Long Non-Coding RNA KCNQ1OT1 Promotes Cataractogenesis via miR-214 and Activation of the Caspase-1 Pathway

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recommendations! Published in 2017 at "Cellular Physiology and Biochemistry"

DOI: 10.1159/000477330

Abstract: Background/Aims: KCNQ1OT1 regulates the expression of tissue-specific imprinted genes within the Kcnq1 domain. Imprinted genes are positive regulators of apoptosis, one of the forms of cell death related to cataract formation, and thus may provide… read more here.

Keywords: caspase; cataract formation; non coding; expression ... See more keywords
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LncRNA KCNQ1OT1 attenuates sepsis-induced myocardial injury via regulating miR-192-5p/XIAP axis

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recommendations! Published in 2020 at "Experimental Biology and Medicine"

DOI: 10.1177/1535370220908041

Abstract: Myocardial dysfunction is a prime cause of death in sepsis. This study is to delve into the function of lncRNA KCNQ1OT1 in myocardial injury induced by sepsis. Sepsis-induced myocardial injury model in rat was initiated… read more here.

Keywords: sepsis; myocardial injury; kcnq1ot1; mir 192 ... See more keywords
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LncRNA KCNQ1OT1 promotes cell proliferation, migration and invasion via regulating miR-129-5p/JAG1 axis in non-small cell lung cancer

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recommendations! Published in 2020 at "Cancer Cell International"

DOI: 10.1186/s12935-020-01225-8

Abstract: Background Non-small cell lung cancer (NSCLC) is the most deadly cancer worldwide. LncRNA KCNQ1OT1 has been reported to be involved in the progression of various tumors, including NSCLC. However, the precise mechanism of KCNQ1OT1 in… read more here.

Keywords: jag1; mir 129; kcnq1ot1; cell ... See more keywords