Degradable cationic polyesters via ring-opening copolymerization of valerolactones as nanocarriers for the gene delivery.
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DOI: 10.1016/j.bioorg.2021.105299
Abstract: The development of cationic polymers as non-viral gene vectors has been hurdled by their high toxicity, thus degradable and biocompatible polymers are urgently demanded. Herein, five polyesters (B3a-B3e) were synthesized based on the ring-opening copolymerization… read more here.
Keywords: dope; ring opening; cationic polyesters; opening copolymerization ... See more keywords