Assessing the role of ketogenic dietary therapy in ring chromosome 20 syndrome: A patient‐led approach
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DOI: 10.1002/epi4.12387
Abstract: Ring chromosome 20 syndrome (r(20)) is an ultra‐rare disease characterized by drug‐refractory epilepsy, cognitive impairment, and behavioral problems. Nonpharmacological treatments alongside antiepileptic drugs early after diagnosis may help reduce seizure frequency and preserve cognition. Ketogenic… read more here.
Keywords: ketogenic dietary; dietary therapy; ring chromosome; kdt ... See more keywords
Mechanistic Studies of the Multiple Myeloma and Melanoma Cell-Selective Toxicity of the Rpn13-Binding Peptoid KDT-11.
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DOI: 10.1016/j.chembiol.2020.08.008
Abstract: We previously reported a peptoid ligand for the proteasomal ubiquitin receptor Rpn13 called KDT-11 and demonstrated that this compound is toxic to multiple myeloma cells, but not non-malignant cells. Here, we show that KDT-11 decreases… read more here.
Keywords: studies multiple; kdt; multiple myeloma; mechanistic studies ... See more keywords
Association of hypercalciuria with vitamin D supplementation in patients undergoing ketogenic dietary therapy
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DOI: 10.3389/fnut.2022.970467
Abstract: Background Ketogenic dietary therapy (KDT) is used as an effective treatment for epilepsy. However, KDT carries the risk of bone health deterioration; therefore, vitamin D supplementation is required. Vitamin D replacement therapy in KDT has… read more here.
Keywords: hypercalciuria; therapy; vitamin supplementation; level ... See more keywords