Articles with "kea" as a keyword



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KEA-1010, a ketamine ester analogue, retains analgesic and sedative potency but is devoid of Psychomimetic effects

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Published in 2019 at "BMC Pharmacology & Toxicology"

DOI: 10.1186/s40360-019-0374-y

Abstract: BackgroundKetamine, a widely used anaesthetic and analgesic agent, is known to improve the analgesic efficacy of opioids and to attenuate central sensitisation and opioid-induced hyperalgesia. Clinical use is, however, curtailed by unwanted psychomimetic effects thought… read more here.

Keywords: tail flick; 1010 ketamine; injection; kea 1010 ... See more keywords