Articles with "keap1 pgam5" as a keyword



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Negative feedback system to maintain cell ROS homeostasis: KEAP1-PGAM5 complex senses mitochondrially generated ROS to induce mitophagy

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Published in 2022 at "Autophagy"

DOI: 10.1080/15548627.2021.2024702

Abstract: ABSTRACT If cellular reactive oxygen species (ROS) production surpasses the intracellular antioxidant capacity, thus altering the ROS homeostasis, the cell needs to eradicate faulty mitochondria responsible for these excessive ROS. We have shown that even… read more here.

Keywords: pgam5; keap1 pgam5; ros homeostasis; pgam5 complex ... See more keywords