Dimeric Artesunate Glycerophosphocholine Conjugate Nano-Assemblies as Slow-Release Antimalarials to Overcome Kelch 13 Mutant Artemisinin Resistance
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DOI: 10.1128/aac.02065-21
Abstract: Current best practice for the treatment of malaria relies on short half-life artemisinins that are failing against emerging Kelch 13 mutant parasite strains. Here, we introduce a liposome-like self-assembly of a dimeric artesunate glycerophosphocholine conjugate… read more here.
Keywords: kelch mutant; artesunate glycerophosphocholine; mutant artemisinin; kelch ... See more keywords