Fitness Costs and the Rapid Spread of kelch13-C580Y Substitutions Conferring Artemisinin Resistance
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DOI: 10.1128/aac.00605-18
Abstract: Fitness costs are key determinants of whether drug resistance alleles establish and how fast they spread within populations. More than 125 different kelch13 alleles, each containing a different amino acid substitution, have arisen in Southeast… read more here.
Keywords: c580y; rapid spread; kelch13; fitness costs ... See more keywords