Naturally Acquired Kelch13 Mutations in Plasmodium falciparum Strains Modulate In Vitro Ring-Stage Artemisinin-Based Drug Tolerance and Parasite Survival in Response to Hyperoxia
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DOI: 10.1128/spectrum.01282-21
Abstract: Artemisinin-based combination therapy (ACT) for treating malaria is under intense scrutiny following treatment failures in the Greater Mekong subregion of Asia. This is further compounded by the potential for extensive loss of life if treatment… read more here.
Keywords: artemisinin based; tolerance; kelch13 mutations; treatment ... See more keywords