Keloid pathophysiology: fibroblast or inflammatory disorders?
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DOI: 10.1016/j.jpra.2019.09.004
Abstract: Background: Keloids are defined as a benign dermal fibroproliferative disorder with no malignant potential. They tend to occur following trivial trauma or any form of trauma in genetically predisposed individuals. Keloids are known to grow… read more here.
Keywords: keloid formation; pathophysiology; inflammatory; pathophysiology fibroblast ... See more keywords
From genetics to epigenetics: new insights into keloid scarring
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DOI: 10.1111/cpr.12326
Abstract: Keloid scarring is a dermal fibroproliferative response characterized by excessive and progressive deposition of collagen; aetiology and molecular pathology underlying keloid formation and progression remain unclear. Genetic predisposition is important in the pathogenic processes of… read more here.
Keywords: genetics epigenetics; keloid formation; genetics; epigenetics new ... See more keywords
Macrophages of the M1 and M2 types play a role in keloids pathogenesis
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DOI: 10.1111/iwj.13834
Abstract: The pathophysiology of keloid formation is unknown, however, macrophages are thought to play a role in keloid formation. Understanding the mechanism(s) of keloid development might be crucial in developing a new treatment regimen for keloids.… read more here.
Keywords: role; keloid formation; study; play role ... See more keywords
Different properties of skin of different body sites: The root of keloid formation?
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DOI: 10.1111/wrr.12574
Abstract: The purpose of this study was to examine extracellular matrix composition, vascularization, and immune cell population of skin sites prone to keloid formation. Keloids remain a complex problem, posing esthetical as well as functional difficulties… read more here.
Keywords: properties skin; extracellular matrix; keloid formation; matrix composition ... See more keywords
Wubeizi Ointment Suppresses Keloid Formation through Modulation of the mTOR Pathway
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DOI: 10.1155/2020/3608372
Abstract: Background Wubeizi (Rhus chinensis Mill.) ointment has been shown as an effective treatment for keloids. However, the protective mechanisms of Wubeizi ointment are not fully understood. The mammalian target of rapamycin (mTOR) has been demonstrated… read more here.
Keywords: formation modulation; keloid formation; mtor; wubeizi ointment ... See more keywords