The reduced susceptibility of mouse keratinocytes to retinoic acid may be involved in the keratinization of oral and esophageal mucosal epithelium
Sign Up to like & getrecommendations! Published in 2020 at "Histochemistry and Cell Biology"
DOI: 10.1007/s00418-020-01845-1
Abstract: Keratinocytes take up serum-derived retinol (vitamin A) and metabolize it to all- trans -retinoic acid (atRA), which binds to the nuclear retinoic acid receptor (RAR). We previously reported that serum-affected keratinocyte differentiation and function; namely,… read more here.
Keywords: epithelium; mucosal; keratinization; mouse keratinocytes ... See more keywords
The KEAP1/NRF2 Signaling Pathway in Keratinization
Sign Up to like & getrecommendations! Published in 2020 at "Antioxidants"
DOI: 10.3390/antiox9080751
Abstract: Keratinization is a tissue adaptation, but aberrant keratinization is associated with skin disorders such as ichthyoses, atopic dermatitis, psoriasis, and acne. The disease phenotype stems from the interaction between genes and the environment; therefore, an… read more here.
Keywords: keap1 nrf2; pathway keratinization; nrf2 signaling; signaling pathway ... See more keywords
Identifying Key Regulators of Keratinization in Lung Squamous Cell Cancer Using Integrated TCGA Analysis
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15072066
Abstract: Simple Summary Keratins are the intermediate filament-forming proteins of epithelial cells that support cell structure and tissue homeostasis. In lung squamous cell cancer, keratins are frequently used as diagnostic tumor markers. However, several studies have… read more here.
Keywords: cell; squamous cell; analysis; keratinization ... See more keywords