The sequence kernel association test for multicategorical outcomes.
Sign Up to like & getrecommendations! Published in 2023 at "Genetic epidemiology"
DOI: 10.1002/gepi.22527
Abstract: Disease heterogeneity is ubiquitous in biomedical and clinical studies. In genetic studies, researchers are increasingly interested in understanding the distinct genetic underpinning of subtypes of diseases. However, existing set-based analysis methods for genome-wide association studies… read more here.
Keywords: multicategorical outcomes; sequence kernel; kernel association; test multicategorical ... See more keywords
The sequence kernel association test for the proportional odds model
Sign Up to like & getrecommendations! Published in 2025 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btaf304
Abstract: Abstract Motivation The Sequence Kernel Association Test (SKAT) and its extensions are the most popular methods for studying the association between phenotypes and a set of single nucleotide polymorphisms. Their practical application is very wide,… read more here.
Keywords: kernel association; test; association; association test ... See more keywords