[Practical aspects of ketamine treatment-Safety, combination treatment and comorbidities].
Sign Up to like & getrecommendations! Published in 2022 at "Der Nervenarzt"
DOI: 10.1007/s00115-021-01260-4
Abstract: BACKGROUND Although multiple studies and meta-analyses have documented the rapid antidepressive efficacy of ketamine, there are numerous questions regarding the practical use in the clinical routine that are still unanswered. OBJECTIVE Based on personal clinical… read more here.
Keywords: treatment; depression; ketamine treatment; combination treatment ... See more keywords
Effects of ketamine treatment on cocaine-induced reinstatement and disruption of functional connectivity in unanesthetized rhesus monkeys
Sign Up to like & getrecommendations! Published in 2019 at "Psychopharmacology"
DOI: 10.1007/s00213-019-05204-4
Abstract: RationaleSubstance use disorders are characterized by a loss of executive control over reward-based decision-making, and disruption of fronto-striatal connectivity has been implicated in this process. Sub-anesthetic ketamine has recently been shown to bolster fronto-striatal connectivity… read more here.
Keywords: rhesus; treatment; cocaine; ketamine treatment ... See more keywords
P11 (S100A10) as a potential predictor of ketamine response in patients with SSRI-resistant depression.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2021.04.055
Abstract: BACKGROUND Ketamine can act as antidepressant in patients with major depressive disorder (MDD) who are treatment-resistant. P11 has been implicated in ketamine's mechanism of action and proposed as biomarker for treatment response to other antidepressants.… read more here.
Keywords: response; treatment; ketamine; p11 levels ... See more keywords
Ketamine in the Treatment of Delusions: A Review of the Evidence
Sign Up to like & getrecommendations! Published in 2023 at "CNS Spectrums"
DOI: 10.1017/s1092852923002031
Abstract: Abstract Introduction Delusions are defined as fixed false beliefs that are not within normal parameters of society, culture, or religion that can be part of psychotic or mood disorders. They can be difficult to treat… read more here.
Keywords: ketamine treatment; ketamine; psychotic symptoms; treatment delusions ... See more keywords
Volumetric changes in subcortical structures following repeated ketamine treatment in patients with major depressive disorder: a longitudinal analysis
Sign Up to like & getrecommendations! Published in 2020 at "Translational Psychiatry"
DOI: 10.1038/s41398-020-00945-9
Abstract: Abnormal subcortical structures have been associated with major depressive disorder (MDD) and could be reversed by antidepressant treatment. To date no study has examined the relationship between subcortical volumes and repeated ketamine treatment. The current… read more here.
Keywords: depressive disorder; treatment; major depressive; repeated ketamine ... See more keywords
Adjunct ketamine treatment effects on treatment-resistant depressive symptoms in chronic treatment-resistant schizophrenia patients are short-term and disassociated from regional homogeneity changes in key brain regions – a pilot study
Sign Up to like & getrecommendations! Published in 2019 at "Psychiatry and Clinical Psychopharmacology"
DOI: 10.1080/24750573.2019.1699726
Abstract: ABSTRACT BACKGROUND: To investigate the effects of adjunct ketamine treatment on depressive symptoms and brain activity in chronic treatment-resistant schizophrenia (CTRS) patients with treatment-resistant depressive (TRD) symptoms. METHODS: Calgary Depression Scale for Schizophrenia (CDSS), positive… read more here.
Keywords: adjunct ketamine; treatment resistant; treatment; ctrs patients ... See more keywords
Use of Staging Models for Treatment-Resistant Depression Is Not Helpful in Predicting Nonresponse to Acute Intravenous Ketamine Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Psychopharmacology"
DOI: 10.1097/jcp.0000000000001524
Abstract: Abstract Background Some staging models for treatment-resistant depression (TRD) have been developed in the attempt to predict treatment outcome, in particular with electroconvulsive therapy. However, these models have not been tested in predicting clinical outcome… read more here.
Keywords: staging models; ketamine treatment; intravenous ketamine; treatment ... See more keywords
Ethnoracial Inclusion in Clinical Trials of Ketamine in the Treatment of Mental Health Disorders.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of studies on alcohol and drugs"
DOI: 10.15288/jsad.2022.83.596
Abstract: OBJECTIVE Despite strong evidence for the safety and efficacy of ketamine in the treatment of mood disorders, the enrollment of Black, Indigenous, and People of Color (BIPOC) has not been a focus of this research.… read more here.
Keywords: health; clinical trials; ketamine treatment; inclusion ... See more keywords
“This Is Something That Changed My Life”: A Qualitative Study of Patients' Experiences in a Clinical Trial of Ketamine Treatment for Alcohol Use Disorders
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2021.695335
Abstract: Background: The therapeutic benefits of ketamine have been demonstrated for a variety of psychiatric disorders. However, the role of ketamine induced psychoactive experiences in mediating the therapeutic effects is unclear. Despite the growing quantitative research… read more here.
Keywords: trial; ketamine; ketamine infusions; alcohol ... See more keywords
Comment on Keeler et al. Ketamine as a Treatment for Anorexia Nervosa: A Narrative Review. Nutrients 2021, 13, 4158
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14102118
Abstract: Anorexia Nervosa (AN) represents a difficult therapeutic challenge, with up to 4% prevalence among females and increasing incidence among youth [...]. read more here.
Keywords: anorexia nervosa; comment keeler; ketamine treatment; keeler ketamine ... See more keywords
Ketamine suppresses the proliferation of rat C6 glioma cells.
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DOI: 10.3892/ol.2017.6806
Abstract: The present study investigated the effects of N-methyl-D-aspartate receptor (NMDAR) antagonist ketamine, on the growth of gliomas. To analyze the effects of ketamine treatment, rat C6 glioma cells arising from astrocytes, and RNB cells representing… read more here.
Keywords: glioma; proliferation; glioma cells; cell ... See more keywords