Reversibility of the catalytic ketonization of carboxylic acids and of beta-keto acids decarboxylation
Sign Up to like & getrecommendations! Published in 2018 at "Catalysis Communications"
DOI: 10.1016/j.catcom.2018.04.002
Abstract: Abstract Decarboxylation of beta-keto acids in enzymatic and heterogeneous catalysis has been considered in the literature as an irreversible reaction due to a large positive entropy change. We report here experimental evidence for its reversibility… read more here.
Keywords: reversibility; beta keto; decarboxylation; carboxylic acids ... See more keywords
Synthesis of quinazolin-4(3H)-ones via electrochemical decarboxylative cyclization of α‑keto acids with 2-aminobenzamides
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Catalysis"
DOI: 10.1016/j.mcat.2020.111345
Abstract: Abstract Herein, an environmentally benign electrochemical protocol has been disclosed for the synthesis of quinazolin-4(3H)-one derivatives from readily available α‑keto acids and 2-aminobenzamides. This decarboxylative cyclization process proceeds conveniently in the absence of any homogeneous… read more here.
Keywords: synthesis quinazolin; decarboxylative cyclization; acids aminobenzamides; keto acids ... See more keywords
Nickel-Catalyzed Asymmetric Hydrogenation of γ-Keto Acids, Esters, and Amides to Chiral γ-Lactones and γ-Hydroxy Acid Derivatives.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00826
Abstract: A highly efficient asymmetric hydrogenation of a series of γ-keto acid derivatives, including γ-keto acids, esters, and amides, using a Ni-(R,R)-QuinoxP* complex as the catalyst has been developed to afford chiral γ-hydroxy acid derivatives with… read more here.
Keywords: esters amides; asymmetric hydrogenation; acids esters; keto ... See more keywords
Calcium(II)-Catalyzed Reductive Amination of Biomass-Derived Keto Acids to Functionalized Lactams under Solvent-Free Conditions.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00676
Abstract: Direct access to the polyfluorinated lactams through Ca(NTf2)2 catalyzed by either the reductive amination of biomass-derived keto acids with amines or the reductive amination of amino acids with carbonyl derivatives under solvent-free conditions is realized.… read more here.
Keywords: biomass derived; amination biomass; derived keto; reductive amination ... See more keywords
Decarbonylative Coupling of α-Keto Acids and Ynamides for Synthesis of β-Keto Imides.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b01302
Abstract: A novel decarbonylative coupling of α-keto acids and ynamides with extrusion of CO for synthesis of β-keto imides is reported. This process features mild reaction conditions, a broad substrate scope, and high efficiency. An isotope-labeling… read more here.
Keywords: decarbonylative coupling; acids ynamides; synthesis keto; keto ... See more keywords