Efficient sulfonylation of ketones with sodium sulfinates for the synthesis of β-keto sulfones
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DOI: 10.1016/j.tetlet.2018.09.049
Abstract: Abstract The oxidative sulfonylation of ketones with sodium sulfinates as the sulfone source and DMSO as the oxidant is reported. A series of β-keto sulfones were obtained in good to excellent yields. The advantages of… read more here.
Keywords: sodium sulfinates; sulfonylation ketones; ketones sodium; keto sulfones ... See more keywords
Synthesis of β-keto sulfones via a multicomponent reaction through sulfonylation and decarboxylation
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DOI: 10.1039/c7qo00026j
Abstract: A copper(I)-catalyzed synthesis of β-keto sulfones through a multicomponent reaction of aryldiazonium tetrafluoroborates, 3-arylpropiolic acids, sulfur dioxide, and water was developed. This reaction proceeds through a tandem radical process, and the sulfonyl radical, generated from… read more here.
Keywords: multicomponent reaction; sulfonylation decarboxylation; synthesis keto; keto ... See more keywords
Metal-free hydrosulfonylation of α,β-unsaturated ketones: synthesis and application of γ-keto sulfones
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DOI: 10.1039/d2ra06784f
Abstract: γ-Keto sulfones are versatile building blocks and valuable intermediates in organic synthesis and pharmaceutical chemistry. Motivated by their excellent properties, we herein report a green, convenient, metal-free hydrosulfonylation method for a variety of ynones, vinyl… read more here.
Keywords: metal free; synthesis; keto sulfones; keto ... See more keywords
Facile Synthesis of β-Keto Sulfones Employing Fenton’s Reagent in DMSO
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DOI: 10.1055/s-0036-1589151
Abstract: A new facile method for the synthesis of β-keto sulfones employing xanthates, DMSO, and Fenton’s reagent is described. The reaction proceeds under very mild conditions providing a cost-effective straightforward approach to various β-keto sulfones in… read more here.
Keywords: fenton reagent; synthesis keto; keto; keto sulfones ... See more keywords
Hydrogenation of β-Keto Sulfones to β-Hydroxy Sulfones with Alkyl Aluminum Compounds: Structure of Intermediate Hydroalumination Products
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DOI: 10.3390/molecules27072357
Abstract: β-Hydroxy sulfones are important in organic synthesis. The simplest method of β-hydroxy sulfones synthesis is the hydrogenation of β-keto sulfones. Herein, we report the reducing properties of alkyl aluminum compounds R3Al (R = Et, i-Bu,… read more here.
Keywords: alkyl aluminum; hydrogenation keto; aluminum compounds; hydroxy sulfones ... See more keywords