Highly diastereo- and enantioselective C2 addition of 5H-oxazol-4-ones to γ-keto-α,β-unsaturated esters.
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DOI: 10.1039/d3cc00554b
Abstract: The direct C2-addition of 5H-oxazol-4-ones to γ-keto-α,β-unsaturated esters catalyzed by a chiral squaramide has been achieved. Diverse highly functionalized γ-keto esters bearing a C2-oxazolone at the α-position were afforded in high yields with excellent stereoselectivities… read more here.
Keywords: ones keto; keto unsaturated; addition oxazol; unsaturated esters ... See more keywords