Mutagenicity of 7-ketocholesterol in CHO cells: the role of lipid peroxidation.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology"
DOI: 10.1016/j.tox.2020.152587
Abstract: As an important cholesterol oxide, 7-ketocholesterol plays a deleterious role in the occurrence of cancer. Although the fact had been proved that 7-ketocholesterol could induce several biological phenomena, including apoptosis, DNA damage, et al., this… read more here.
Keywords: role; cho cells; ketocholesterol; lipid peroxidation ... See more keywords
Abstract A50: 7-Ketocholesterol loaded-phosphatidylserine liposome induces cell death, autophagy, and growth inhibition of melanoma and breast adenocarcinoma
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DOI: 10.1158/1557-3265.tcm17-a50
Abstract: Background: The exposure of phosphatidylserine (PS) is one of the first steps of programmed cell death. Phagocytosis on cancer microenvironment is well described in tumors and is associated with malignancy and poor prognosis. Tumor associated… read more here.
Keywords: melanoma; breast adenocarcinoma; ketocholesterol; autophagy ... See more keywords
7-Ketocholesterol-Induced Micro-RNA-107-5p Increases Number and Activity of Osteoclasts by Targeting MKP1
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DOI: 10.3390/ijms23073697
Abstract: Osteoclasts (OCs), which are responsible for bone resorption, play a critical role in cholesterol-induced bone loss and recent studies have suggested that various micro-RNAs (miRs) contribute to modulating OCs. We hypothesized that 7-ketocholesterol (7-KC), a… read more here.
Keywords: induced micro; ketocholesterol; number; mir 107 ... See more keywords