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Published in 2020 at "International Journal of Cancer"
DOI: 10.1002/ijc.33017
Abstract: Dear editor, In an interesting letter published recently in this journal, Drs Israël and Schwartz hypothesize that the breakdown of ketone bodies is a tumor cell's “unique source of mitochondrial acetyl CoA”. They propose to…
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Keywords:
tumor;
coa;
acetyl coa;
cell ... See more keywords
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Published in 2017 at "International Journal of Legal Medicine"
DOI: 10.1007/s00414-017-1741-0
Abstract: Diabetic ketoacidosis (DKA) is a metabolic complication of diabetes mellitus that takes a lethal course if untreated. In this way relevant to forensic medicine, secure diagnosis of DKA usually involves the evidence of elevated levels…
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Keywords:
medicine;
postmortem mrs;
diabetic ketoacidosis;
ketone bodies ... See more keywords
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Published in 2018 at "Journal of forensic and legal medicine"
DOI: 10.1016/j.jflm.2018.07.009
Abstract: We report a fetal loss following maternal ketoacidosis in a case of cryptic pregnancy. Biochemical analysis of peripheral blood revealed highly elevated levels of beta-hydroxybutyrate (BHB) in the mother (9.2 mmol/l) and the fetus (4.2 mmol/l). Fetal…
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Keywords:
detection;
fetal ketoacidosis;
ketoacidosis;
case ... See more keywords
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Published in 2019 at "Pharmacological research"
DOI: 10.1016/j.phrs.2019.104500
Abstract: Ketone bodies are traditionally viewed as metabolic substrates in carbohydrate restriction and are applied in the treatment of epilepsy and other neurodegenerative diseases. Recently, people have paid more attention to its application in the treatment…
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Keywords:
roles ketone;
multi dimensional;
biology;
cancer ... See more keywords
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Published in 2023 at "European heart journal"
DOI: 10.1093/eurheartj/ehad087
Abstract: AIMS Ketone bodies (KB) are an important alternative metabolic fuel source for the myocardium. Experimental and human investigations suggest that KB may have protective effects in patients with heart failure. This study aimed to examine…
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Keywords:
ketone bodies;
rate;
mortality;
cvd ... See more keywords
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Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/hjh.0000000000003243
Abstract: Hypertension is the most important risk factor for the development of terminal cardiovascular diseases, such as heart failure, chronic kidney disease, and atherosclerosis. Lifestyle interventions to lower blood pressure are generally desirable prior to initiating…
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Keywords:
janus face;
ketone;
ketone bodies;
side effects ... See more keywords
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3
Published in 2023 at "Aging cell"
DOI: 10.1111/acel.13833
Abstract: Accumulating evidence suggests health benefits of ketone bodies, and especially for longevity. However, the precise role of endogenous ketogenesis in mammalian life span, and the safety and efficacy of the long-term exogenous supplementation of ketone…
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Keywords:
life span;
edged sword;
ketone bodies;
mammalian life ... See more keywords
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Published in 2022 at "Cancer Science"
DOI: 10.1111/cas.15667
Abstract: The Mondo family transcription factor MondoA plays a pivotal role in sensing metabolites, such as glucose, glutamine, and lactic acid, to regulate glucose metabolism and cell proliferation. Ketone bodies are important signals for reducing glucose…
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Keywords:
mondoa;
ketone bodies;
glucose uptake;
phosphorylation ... See more keywords
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Published in 2023 at "Circulation Research"
DOI: 10.1161/circresaha.123.321872
Abstract: The ketone bodies beta-hydroxybutyrate and acetoacetate are hepatically produced metabolites catabolized in extrahepatic organs. Ketone bodies are a critical cardiac fuel and have diverse roles in the regulation of cellular processes such as metabolism, inflammation,…
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Keywords:
metabolism;
ketone;
heart metabolic;
ketone bodies ... See more keywords
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Published in 2021 at "Veterinary World"
DOI: 10.14202/vetworld.2021.1492-1503
Abstract: Ketosis is the most common metabolic disease in high-performance dairy cows during the first 6-8 weeks of lactation. Its main symptoms include an excessive amount of so-called ketone bodies in a cow’s body fluids. Ketone…
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Keywords:
body fluids;
bodies causes;
ketosis;
ketone bodies ... See more keywords
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Published in 2020 at "eNeuro"
DOI: 10.1523/eneuro.0303-20.2020
Abstract: Abstract The ketogenic diet (KD) has been successfully used for a century for treating refractory epilepsy and is currently seen as one of the few viable approaches to the treatment of a plethora of metabolic…
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Keywords:
action ketones;
brain glucose;
ketone bodies;
glucose sparing ... See more keywords