Synthesis, characterization, molecular docking, analgesic, antiplatelet and anticoagulant effects of dibenzylidene ketone derivatives
Sign Up to like & getrecommendations! Published in 2018 at "Chemistry Central Journal"
DOI: 10.1186/s13065-018-0507-1
Abstract: In this study dibenzylidene ketone derivatives (2E,5E)-2-(4-methoxybenzylidene)-5-(4-nitrobenzylidene) cyclopentanone (AK-1a) and (1E,4E)-4-(4-nitrobenzylidene)-1-(4-nitrophenyl) oct-1-en-3-one (AK-2a) were newly synthesized, inspired from curcuminoids natural origin. Novel scheme was used for synthesis of AK-1a and AK-2a. The synthesized compounds were… read more here.
Keywords: ketone derivatives; saline group; 001 saline; analgesic antiplatelet ... See more keywords
Stereoselective Synthesis of δ- and ε-Amino Ketone Derivatives from N-tert-Butanesulfinyl Aldimines and Functionalized Organolithium Compounds
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DOI: 10.3390/molecules26216503
Abstract: The addition of functionalized organolithium compounds derived from 5-chloro-2-methoxy-1-pentene and 6-chloro-2-methoxy-1-hexene to N-tert-butanesulfinyl aldimines imines, and a subsequent hydrolysis of the enol ether moiety, yielded different δ- and ε-amino ketone derivatives, respectively, in moderate yields… read more here.
Keywords: ketone derivatives; amino ketone; tert butanesulfinyl; butanesulfinyl aldimines ... See more keywords