Base-catalyzed addition of silylacetylenes to ketones: a route to protected tertiary propargyl alcohols
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DOI: 10.1039/d3qo00579h
Abstract: The base-catalyzed addition of alkynylsilanes to ketone derivatives enables the formation of various silyl-protected propargylic alcohols. Commercially available and inexpensive potassium bis(trimethylsilyl)amide (KHMDS) serves as an efficient transition metal-free catalyst... read more here.
Keywords: silylacetylenes ketones; base catalyzed; catalyzed addition; ketones route ... See more keywords