Engineering ketoreductases for the enantioselective synthesis of chiral alcohols.
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DOI: 10.1039/d3cc01474f
Abstract: The use of engineered ketoreductases (KREDS), both as whole microbial cells and isolated enzymes, in the highly enantiospecific reduction of prochiral ketones is reviewed. The homochiral alcohol products are key intermediates in, for example, pharmaceuticals… read more here.
Keywords: engineering ketoreductases; enantioselective synthesis; ketoreductases enantioselective; chiral alcohols ... See more keywords