Structural characterization and Kemp eliminase activity of the Mycobacterium smegmatis Ketosteroid Isomerase.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.05.007
Abstract: The Kemp elimination reaction, involving the ring-opening of benzoxazole and its derivatives under the action of natural enzymes or chemical catalysts, has been of interest to researchers since its discovery. Because this reaction does not… read more here.
Keywords: structural characterization; ketosteroid isomerase; kemp elimination; mycobacterium smegmatis ... See more keywords
Marmoset glutathione transferases with ketosteroid isomerase activity
Sign Up to like & getrecommendations! Published in 2021 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2021.101078
Abstract: The common marmoset Callithrix jacchus encodes two glutathione transferase (GST) enzymes with ketosteroid double-bond isomerase activity. The most active enzyme is CjaGST A3-3 showing a specific activity with 5-androsten-3,17-dione (Δ5-AD) of 62.1 ± 1.8 μmol… read more here.
Keywords: isomerase activity; cjagst; ketosteroid isomerase; activity ... See more keywords
Direct Look at the Electric Field in Ketosteroid Isomerase and Its Variants
Sign Up to like & getrecommendations! Published in 2020 at "ACS Catalysis"
DOI: 10.1021/acscatal.0c02795
Abstract: Enzymes catalyze a number of reactions with high efficiency and stereoselectivity. It is thought that strong, direct, and permanent electric fields within the active site of the enzyme contribute t... read more here.
Keywords: isomerase variants; direct look; field ketosteroid; ketosteroid isomerase ... See more keywords