Adipose tissue proteomic analysis in ketotic or healthy Holstein cows in early lactation1.
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DOI: 10.1093/jas/skz132
Abstract: Ketosis is a major metabolic disorder of high-yielding dairy cows during the transition period. Although metabolic adaptations of the adipose tissue are critical for a successful transition, beyond lipolysis, alterations within adipose tissue during ketosis… read more here.
Keywords: ketotic cows; metabolism; ketosis; tissue ... See more keywords
Enhanced mitochondrial dysfunction and oxidative stress in the mammary gland of cows with clinical ketosis.
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DOI: 10.3168/jds.2020-19964
Abstract: Ketosis is a common metabolic disorder in high-producing dairy cows during the peripartal period. Negative energy balance leads to increased circulating levels of nonesterified fatty acids (NEFA) and β-hydroxybutyrate (BHB), consequently increasing the risk of… read more here.
Keywords: ketotic cows; ketosis; mammary gland; stress ... See more keywords
Disruption of endoplasmic reticulum homeostasis exacerbates liver injury in clinically ketotic cows.
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DOI: 10.3168/jds.2021-20238
Abstract: Disruption of endoplasmic reticulum (ER) homeostasis, a condition termed "ER stress," contributes to the development of liver injury in nonruminants. Because liver injury is a prominent pathological feature associated with overproduction of ketone bodies in… read more here.
Keywords: ketotic cows; clinically ketotic; bhb; stress ... See more keywords