Identification of Key Biomarkers for Systemic Lupus Erythematosus Progression and Therapy Response: A Bulk RNA‐Sequencing‐Based Bioinformatics Study
Sign Up to like & getrecommendations! Published in 2025 at "Brain and Behavior"
DOI: 10.1002/brb3.71098
Abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs and has a higher prevalence in women of reproductive age. The increasing global incidence of this disease poses a significant public health… read more here.
Keywords: key biomarkers; identification key; lupus erythematosus; systemic lupus ... See more keywords
Identification of key biomarkers in diabetic nephropathy via bioinformatic analysis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28155
Abstract: Diabetic nephropathy (DN) is a major cause of end‐stage renal disease. Although intense efforts have been made to elucidate the pathogenesis, the molecular mechanisms of DN remain to be clarified. To identify the candidate genes… read more here.
Keywords: identification key; analysis; hub genes; biomarkers diabetic ... See more keywords
Identification of key biomarkers of the glomerulus in focal segmental glomerulosclerosis and their relationship with immune cell infiltration based on WGCNA and the LASSO algorithm
Sign Up to like & getrecommendations! Published in 2023 at "Renal Failure"
DOI: 10.1080/0886022x.2023.2202264
Abstract: Abstract Objective The aim of our study was to identify key biomarkers of glomeruli in focal glomerulosclerosis (FSGS) and analyze their relationship with the infiltration of immune cells. Methods The expression profiles (GSE108109 and GSE200828)… read more here.
Keywords: infiltration; cell infiltration; relationship; immune cell ... See more keywords
P125 MIG (CXCL9) and IL22 are key biomarkers that discriminates between paediatric IBD patients and non-IBD patients in a novel biomarker model
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjad212.0255
Abstract: The current gold standard for diagnosis of Inflammatory bowel disease (IBD) is based on clinical and endoscopic evaluation as well as histologic and radiologic evaluation. However, endoscopic evaluation can be uncomfortable and carry some risks,… read more here.
Keywords: ibd; ibd patients; il22; key biomarkers ... See more keywords
Transcriptomic characterization of lamb ovaries and oocytes reveals key biomarkers after superovulation.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of animal science"
DOI: 10.1093/jas/skaf193
Abstract: Superovulated prepubertal lambs serve as an important source of oocytes for Juvenile In Vitro Embryo Transfer (JIVET); however, their ovarian response to gonadotropin stimulation markedly differs from that of adult ewes. The ovaries and oocytes… read more here.
Keywords: ovaries oocytes; characterization lamb; key biomarkers; lamb ... See more keywords
Screening and identification of key biomarkers for retinoblastoma
Sign Up to like & getrecommendations! Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000019952
Abstract: Abstract Background: Retinoblastoma (RB) is one of the most common malignant tumors in pediatrics; to clarify the cause of RB, a lot of manpower and material resources have been invested but have not been well… read more here.
Keywords: key biomarkers; screening identification; identification key; occurrence ... See more keywords
Identification of multiomics map and key biomarkers in uveal melanoma with chromosome 3 loss
Sign Up to like & getrecommendations! Published in 2024 at "Annals of Medicine and Surgery"
DOI: 10.1097/ms9.0000000000001585
Abstract: Purpose: Chromosome 3 loss is an independent risk factor for uveal melanoma (UM), but its exact molecular mechanisms remain unclear. This study was designed to investigate the relationship between chromosome 3 loss and molecular alterations… read more here.
Keywords: uveal melanoma; loss; analysis; chromosome loss ... See more keywords
Screening of key biomarkers in osteoporosis: Evidence from bioinformatic analysis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.14450
Abstract: To analyze the expression characteristics of osteoporosis‐related genes by bioinformatics and elucidate the pathogenesis of osteoporosis. read more here.
Keywords: bioinformatic analysis; osteoporosis evidence; key biomarkers; biomarkers osteoporosis ... See more keywords
Characterisation of key biomarkers in diabetic ulcers via systems bioinformatics
Sign Up to like & getrecommendations! Published in 2022 at "International Wound Journal"
DOI: 10.1111/iwj.13900
Abstract: Diabetic ulcers (DUs) are characterised by a high incidence and disability rate. However, its pathogenesis remains elusive. Thus, a deep understanding of the underlying mechanisms for the pathogenesis of DUs has vital implications. The weighted… read more here.
Keywords: hub genes; characterisation key; ulcers via; biomarkers diabetic ... See more keywords
Amyloid-β and Phosphorylated Tau are the Key Biomarkers and Predictors of Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2024 at "Aging and Disease"
DOI: 10.14336/ad.2024.0286
Abstract: Alzheimer’s disease (AD) is a age-related neurodegenerative disease and is a major public health concern both in Texas, US and Worldwide. This neurodegenerative disease is mainly characterized by amyloid-beta (Aβ) and phosphorylated Tau (p-Tau) accumulation… read more here.
Keywords: alzheimer disease; disease; disease amyloid; phosphorylated tau ... See more keywords
Identification of Biomarkers Associated with Hepatocellular Carcinoma Stem Cell Characteristics Based on Co-Expression Network Analysis of Transcriptome Data and Stemness Index.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in eukaryotic gene expression"
DOI: 10.1615/critreveukaryotgeneexpr.2021039692
Abstract: Mounting evidence has revealed the key role of cancer stem cells in hepatocellular carcinoma (HCC) metastasis and therapy resistance, yet the genes maintaining HCC stem cell features remain to be explored. This study aimed to… read more here.
Keywords: biomarkers associated; hcc; stemness; expression ... See more keywords