mTOR Is Key to T Cell Transdifferentiation.
Sign Up to like & getrecommendations! Published in 2019 at "Cell metabolism"
DOI: 10.1016/j.cmet.2019.01.008
Abstract: T cell transdifferentiation to functionally distinct subsets can play a key role in balancing the protective and pathogenic features of the T cell response. In a new study, Karmaus et al. (2019) showed that mTORC1 activity influences… read more here.
Keywords: transdifferentiation; mtor key; key cell; cell ... See more keywords
Investigating key cell types and molecules dynamics in PyMT mice model of breast cancer through a mathematical model
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1009953
Abstract: The most common kind of cancer among women is breast cancer. Understanding the tumor microenvironment and the interactions between individual cells and cytokines assists us in arriving at more effective treatments. Here, we develop a… read more here.
Keywords: mathematical model; cell types; breast cancer; model ... See more keywords
Endothelial Cells as a Key Cell Type for Innate Immunity: A Focused Review on RIG-I Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.951614
Abstract: The vascular endothelium consists of a highly heterogeneous monolayer of endothelial cells (ECs) which are the primary target for bacterial and viral infections due to EC’s constant and close contact with the bloodstream. Emerging evidence… read more here.
Keywords: endothelial cells; immunity; innate immunity; key cell ... See more keywords