Bacoside-A diminishes liver functional enzymes and improves carbohydrate metabolic key enzymes in streptozotocin a rat model of T2DM
Sign Up to like & getrecommendations! Published in 2019 at "Biocatalysis and Agricultural Biotechnology"
DOI: 10.1016/j.bcab.2019.101331
Abstract: Abstract Type 2 diabetes mellitus (T2DM) is a global alarming predominant metabolic disease than other diabetes and incurs substantial burden to public and healthcare systems. Our study is designed to endeavor the valuable effect of… read more here.
Keywords: t2dm; key enzymes; bacoside diminishes; diabetic rats ... See more keywords
The Metabolism and Biotransformation of AFB1: Key enzymes and Pathways.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2022.115005
Abstract: Aflatoxins B1 (AFB1) is a hepatoxic compound produced by Aspergillus flavus and Aspergillus parasiticus, seriously threatening food safety and the health of humans and animals. Understanding the metabolism of AFB1 is important for developing detoxification… read more here.
Keywords: humans animals; metabolism biotransformation; metabolism; biotransformation afb1 ... See more keywords
Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.07.026
Abstract: In this work we describe neurogenic and neuroprotective donepezil-flavonoid hybrids (DFHs), exhibiting nanomolar affinities for the sigma-1 receptor (σ1R) and inhibition of key enzymes in Alzheimer's disease (AD), such as acetylcholinesterase (AChE), 5-lipoxygenase (5-LOX), and monoamine… read more here.
Keywords: key enzymes; donepezil flavonoid; inhibition key; neurogenic neuroprotective ... See more keywords
Lotus aegaeus (Gris.) Boiss and Iberis sempervirens L.: Chemical fingerprints, antioxidant potential, and inhibition activities and docking on key enzymes linked to global health problems
Sign Up to like & getrecommendations! Published in 2018 at "Industrial Crops and Products"
DOI: 10.1016/j.indcrop.2018.04.056
Abstract: Abstract Natural products are gaining much momentum worldwide because they have a broad spectrum of biological effects and present excellent opportunities for bioproducts development. With this fact, this study has been designed to investigate for… read more here.
Keywords: key enzymes; iberis sempervirens; aegaeus gris; lotus aegaeus ... See more keywords
The hexokinases HbHXK2 and 4 are key enzymes involved in glucose metabolism and contribute to rubber productivity in Hevea brasiliensis (para rubber tree)
Sign Up to like & getrecommendations! Published in 2021 at "Industrial Crops and Products"
DOI: 10.1016/j.indcrop.2020.113025
Abstract: Abstract In higher plants, hexokinase (HXK) is a crucial enzyme that phosphorylates glucose, because there is no evidence for the existence of glucokinase (GLK). In the rubber tree laticifers, the phosphorylation of glucose initiates glycolysis… read more here.
Keywords: key enzymes; hevea brasiliensis; hbhxk2 key; rubber tree ... See more keywords
Integrated Metagenomic and Metaproteomic Analyses Unravel Ammonia Toxicity to Active Methanogens and Syntrophs, Enzyme Synthesis, and Key Enzymes in Anaerobic Digestion.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental science & technology"
DOI: 10.1021/acs.est.1c00797
Abstract: During anaerobic digestion, the active microbiome synthesizes enzymes by transcription and translation, and then enzymes catalyze multistep bioconversions of substrates before methane being produced. However, little information is available on how ammonia affects truly active… read more here.
Keywords: key enzymes; enzyme synthesis; anaerobic digestion; synthesis key ... See more keywords
Characterization of key enzymes involved in triacylglycerol biosynthesis in mycobacteria
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-92721-y
Abstract: Phosphatidic acid phosphatase (PAP) catalyzes the dephosphorylation of phosphatidic acid (PA) yielding diacylglycerol (DAG), the lipid precursor for triacylglycerol (TAG) biosynthesis. PAP activity has a key role in the regulation of PA flux towards TAG… read more here.
Keywords: enzymes involved; biosynthesis; key enzymes; characterization key ... See more keywords
Abundance and phylogenetic distribution of eight key enzymes of the phosphorus biogeochemical cycle in grassland soils.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental microbiology reports"
DOI: 10.1111/1758-2229.13159
Abstract: Grassland biomes provide valuable ecosystem services, including nutrient cycling. Organic phosphorus (Po) represents more than half of the total P in soils. Soil microorganisms release organic P through enzymatic processes, with alkaline phosphatases, acid phosphatases… read more here.
Keywords: key enzymes; phylogenetic distribution; abundance; grassland ... See more keywords
Improvement of isoprene production in Escherichia coli by rational optimization of RBSs and key enzymes screening
Sign Up to like & getrecommendations! Published in 2019 at "Microbial Cell Factories"
DOI: 10.1186/s12934-018-1051-3
Abstract: BackgroundAs an essential platform chemical mostly used for rubber synthesis, isoprene is produced in industry through chemical methods, derived from petroleum. As an alternative, bio-production of isoprene has attracted much attention in recent years. Previous… read more here.
Keywords: key enzymes; production; isoprene production; expression ... See more keywords
Parallel comparative proteomics and phosphoproteomics reveal that cattle myostatin regulates phosphorylation of key enzymes in glycogen metabolism and glycolysis pathway
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.24250
Abstract: MSTN-encoded myostatin is a negative regulator of skeletal muscle development. Here, we utilized the gluteus tissues from MSTN gene editing and wild type Luxi beef cattle which are native breed of cattle in China, performed… read more here.
Keywords: key enzymes; glycolysis; metabolism; muscle ... See more keywords
Key Enzymes in Fatty Acid Synthesis Pathway for Bioactive Lipids Biosynthesis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.851402
Abstract: Dietary bioactive lipids, one of the three primary nutrients, is not only essential for growth and provides nutrients and energy for life's activities but can also help to guard against disease, such as Alzheimer's and… read more here.
Keywords: bioactive lipids; dietary bioactive; synthesis; fatty acid ... See more keywords