A key metabolic integrator, coenzyme A, modulates the activity of peroxiredoxin 5 via covalent modification
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-019-03593-w
Abstract: Peroxiredoxins (Prdxs) are antioxidant enzymes that catalyse the breakdown of peroxides and regulate redox activity in the cell. Peroxiredoxin 5 (Prdx5) is a unique member of Prdxs, which displays a wider subcellular distribution and substrate… read more here.
Keywords: integrator coenzyme; key metabolic; activity; via covalent ... See more keywords
Glutaminase 1 regulates the release of extracellular vesicles during neuroinflammation through key metabolic intermediate alpha-ketoglutarate
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-018-1120-x
Abstract: BackgroundExtracellular vesicles (EVs) are important in the intercellular communication of the central nervous system, and their release is increased during neuroinflammation. Our previous data demonstrated an increased release of EVs during HIV-1 infection and immune… read more here.
Keywords: neuroinflammation; key metabolic; gls1; ketoglutarate ... See more keywords
Integrated transcriptomics and metabolomics reveal key metabolic pathway responses in Pistia stratiotes under Cd stress.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of hazardous materials"
DOI: 10.2139/ssrn.4302693
Abstract: Cadmium (Cd) can interfere with plant gene expression, change the content of metabolites and affect plant growth. In this study, untargeted metabolomics (LC-MS) and RNA-Seq sequencing were performed on root tissues of Pistia stratiotes exposed… read more here.
Keywords: transcriptomics metabolomics; pistia stratiotes; stratiotes stress; key metabolic ... See more keywords
Key Metabolic Enzymes Underlying Astrocytic Upregulation of GABAergic Plasticity
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2017.00144
Abstract: GABAergic plasticity is recognized as a key mechanism of shaping the activity of the neuronal networks. However, its description is challenging because of numerous neuron-specific mechanisms. In particular, while essential role of glial cells in… read more here.
Keywords: key metabolic; gabaergic plasticity; gephyrin puncta; metabolic enzymes ... See more keywords
Untargeted Metabolomics Identifies Key Metabolic Pathways Altered by Thymoquinone in Leukemic Cancer Cells
Sign Up to like & getrecommendations! Published in 2020 at "Nutrients"
DOI: 10.3390/nu12061792
Abstract: Thymoquinone (TQ), a naturally occurring anticancer compound extracted from Nigella sativa oil, has been extensively reported to possess potent anti-cancer properties. Experimental studies showed the anti-proliferative, pro-apoptotic, and anti-metastatic effects of TQ on different cancer… read more here.
Keywords: metabolic pathways; key metabolic; cancer cells; cancer ... See more keywords
A Key Metabolic Regulator of Bone and Cartilage Health
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology and Metabolism"
DOI: 10.3803/enm.2022.1443
Abstract: Taurine, a cysteine-derived zwitterionic sulfonic acid, is a common ingredient in energy drinks and is naturally found in fish and other seafood. In humans, taurine is produced mainly in the liver, and it can also… read more here.
Keywords: health; bone; cartilage; key metabolic ... See more keywords