Key mutations in the spike protein of SARS‐CoV‐2 affecting neutralization resistance and viral internalization
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28407
Abstract: To control the ongoing COVID‐19 pandemic, a variety of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccines have been developed. However, the rapid mutations of SARS‐CoV‐2 spike (S) protein may reduce the protective efficacy of… read more here.
Keywords: neutralization; key mutations; protective efficacy; spike protein ... See more keywords
AutoVEM: An automated tool to real-time monitor epidemic trends and key mutations in SARS-CoV-2 evolution
Sign Up to like & getrecommendations! Published in 2021 at "Computational and Structural Biotechnology Journal"
DOI: 10.1016/j.csbj.2021.04.002
Abstract: With the global epidemic of SARS-CoV-2, it is important to effectively monitor the variation, haplotype subgroup epidemic trends and key mutations of SARS-CoV-2 over time. This is of great significance to the development of new… read more here.
Keywords: haplotype subgroup; epidemic trends; time; key mutations ... See more keywords
AutoVEM2: A flexible automated tool to analyze candidate key mutations and epidemic trends for virus
Sign Up to like & getrecommendations! Published in 2021 at "Computational and Structural Biotechnology Journal"
DOI: 10.1016/j.csbj.2021.09.002
Abstract: In our previous work, we developed an automated tool, AutoVEM, for real-time monitoring the candidate key mutations and epidemic trends of SARS-CoV-2. In this research, we further developed AutoVEM into AutoVEM2. AutoVEM2 is composed of… read more here.
Keywords: candidate key; mutations epidemic; automated tool; epidemic trends ... See more keywords