Heterologous Reconstitution of Toxoflavin Biosynthesis Reveals Key Pathway Intermediates and a Cofactor-Independent Oxidase.
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DOI: 10.1021/acs.orglett.3c01000
Abstract: Bacterial azapteridine-containing phytotoxin toxoflavin is a causal agent of rice grain rot. Here, we heterologously reconstitute Bukholderia toxoflavin biosynthesis in Escherichia coli and identify key pathway intermediates, including the hitherto unknown ribityl-dedimethyl-toxoflavin. Furthermore, we characterized… read more here.
Keywords: toxoflavin; toxoflavin biosynthesis; oxidase; pathway intermediates ... See more keywords
Hub Genes and Key Pathway Identification in Colorectal Cancer Based on Bioinformatic Analysis
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DOI: 10.1155/2019/1545680
Abstract: Colorectal cancer (CRC) is one of the most common malignant tumors. The aim of the present study was to identify key genes and pathways to improve the understanding of the mechanism of CRC. GSE87211, including… read more here.
Keywords: analysis; hub genes; colorectal cancer; genes key ... See more keywords
Comparative Transcriptomic Analysis of Biological Process and Key Pathway in Three Cotton (Gossypium spp.) Species Under Drought Stress
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DOI: 10.3390/ijms20092076
Abstract: Drought is one of the most important abiotic stresses that seriously affects cotton growth, development, and production worldwide. However, the molecular mechanism, key pathway, and responsible genes for drought tolerance incotton have not been stated… read more here.
Keywords: three cotton; analysis biological; key pathway; drought stress ... See more keywords