Single-Cell Profiling Identifies Key Pathways Expressed by iPSCs Cultured in Different Commercial Media
Sign Up to like & getrecommendations! Published in 2018 at "iScience"
DOI: 10.1016/j.isci.2018.08.016
Abstract: Summary We assessed the pluripotency of human induced pluripotent stem cells (iPSCs) maintained on an automated platform using StemFlex and TeSR-E8 media. Analysis of transcriptome of single cells revealed similar expression of core pluripotency genes,… read more here.
Keywords: single cell; profiling identifies; key pathways; identifies key ... See more keywords
Identification of key pathways and genes in the progression of silicosis based on WGCNA
Sign Up to like & getrecommendations! Published in 2022 at "Inhalation Toxicology"
DOI: 10.1080/08958378.2022.2102700
Abstract: Abstract Silicosis, induced by inhaling silica particles in workplaces, is one of the most common occupational diseases. The prognosis of silicosis and its consequent fibrosis is extremely poor due to limited treatment modalities and lack… read more here.
Keywords: identification key; silicosis; pathways genes; silicosis fibrosis ... See more keywords
Depigmenting topical therapy based on a synergistic combination of compounds targeting the key pathways involved in melasma pathophysiology
Sign Up to like & getrecommendations! Published in 2023 at "Experimental Dermatology"
DOI: 10.1111/exd.14752
Abstract: Melasma has a complex pathophysiology with different cell types and signalling pathways involved. Paracrine factors secreted by keratinocytes, fibroblasts and endothelial cells act on melanocytes and stimulate melanogenesis. These paracrine factors are involved in the… read more here.
Keywords: combination compounds; involved melasma; pathophysiology; combination ... See more keywords
Identification of Hub Genes and Key Pathways Associated with Two Subtypes of Diffuse Large B-Cell Lymphoma Based on Gene Expression Profiling via Integrated Bioinformatics
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/3574534
Abstract: There is a significant difference in prognosis between the germinal center B-cell (GCB) and activated B-cell (ABC) subtypes of diffuse large B-cell lymphoma (DLBCL). However, the signaling pathways and driver genes involved in these disparate… read more here.
Keywords: key pathways; hub genes; genes key; two subtypes ... See more keywords
Dynamically characterizing individual clinical change by the steady state of disease-associated pathway
Sign Up to like & getrecommendations! Published in 2019 at "BMC Bioinformatics"
DOI: 10.1186/s12859-019-3271-x
Abstract: Along with the development of precision medicine, individual heterogeneity is attracting more and more attentions in clinical research and application. Although the biomolecular reaction seems to be some various when different individuals suffer a same… read more here.
Keywords: state; characterizing individual; key pathways; change ... See more keywords
Identification of key pathways and hub genes in the myogenic differentiation of pluripotent stem cell: a bioinformatics and experimental study
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Orthopaedic Surgery and Research"
DOI: 10.1186/s13018-020-01979-x
Abstract: Background The regeneration of muscle cells from stem cells is an intricate process, and various genes are included in the process such as myoD, mf5, mf6, etc. The key genes and pathways in the differentiating… read more here.
Keywords: key pathways; hub genes; study; differentiation ... See more keywords
Identification of six hub genes and two key pathways in two rat renal fibrosis models based on bioinformatics and RNA-seq transcriptome analyses
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.1035772
Abstract: Renal fibrosis (RF) is the common pathological manifestation and central treatment target of multiple chronic kidney diseases with high morbidity and mortality. Currently, the molecular mechanisms underlying RF remain poorly understood, and exploration of RF-related… read more here.
Keywords: hub targets; rna seq; renal fibrosis; key pathways ... See more keywords
Weighted Gene Co-Expression Network Analysis Reveals Key Pathways and Hub Genes Associated with Successful Grafting in Pecan (Carya illinoinensis)
Sign Up to like & getrecommendations! Published in 2023 at "Forests"
DOI: 10.3390/f14040835
Abstract: Patch budding (bud grafting) is a commonly used method for pecan reproduction; however, the grafting survival rate varies with cultivars. Clarifying the underlying mechanisms of successful grafting is pivotal for graft technique improvement. Here, weighted… read more here.
Keywords: hub genes; gene; successful grafting; analysis ... See more keywords
Key Pathways and Genes of Arabidopsis thaliana and Arabidopsis halleri Roots under Cadmium Stress Responses: Differences and Similarities
Sign Up to like & getrecommendations! Published in 2023 at "Plants"
DOI: 10.3390/plants12091793
Abstract: Cadmium (Cd) is among the world’s major health concerns, as it renders soils unsuitable and unsafe for food and feed production. Phytoremediation has the potential to remediate Cd-polluted soils, but efforts are still needed to… read more here.
Keywords: stress; halleri; cadmium; differences similarities ... See more keywords
Transcriptome sequencing identifies key pathways and genes involved in gastric adenocarcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2018.9370
Abstract: The present study aimed to investigate the key pathways and genes associated with gastric adenocarcinoma via transcriptome sequencing. Five pairs of gastric adenocarcinoma tissue and normal tumor-adjacent tissue were harvested. After sequencing, raw data were… read more here.
Keywords: key pathways; gastric adenocarcinoma; transcriptome sequencing; genes cluster ... See more keywords
Identification of key pathways and genes in nasopharyngeal carcinoma using bioinformatics analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Oncology letters"
DOI: 10.3892/ol.2019.10133
Abstract: Nasopharyngeal carcinoma (NPC) is one of the most common malignancies in the head and neck. The aim of the current study was to identify the key pathways and genes involved in NPC through bioinformatics analysis… read more here.
Keywords: pathways genes; bioinformatics analysis; key pathways; degs ... See more keywords