MicroRNAs role as potential biomarkers and key regulators in melanoma
Sign Up to like & getrecommendations! Published in 2017 at "Genes"
DOI: 10.1002/gcc.22402
Abstract: Malignant melanoma (MM) is a highly aggressive skin cancer with high incidence worldwide. It originates from melanocytes and is characterized by invasion, early metastasis and despite the use of new drugs it is still characterized… read more here.
Keywords: micrornas role; key regulators; role potential; potential biomarkers ... See more keywords
miRNAs as key regulators via targeting the phytohormone signaling pathways during somatic embryogenesis of plants
Sign Up to like & getrecommendations! Published in 2020 at "3 Biotech"
DOI: 10.1007/s13205-020-02487-9
Abstract: Somatic embryogenesis is the regeneration of embryos from the somatic cell via dedifferentiation and redifferentiation without the occurrence of fertilization. A complex network of genes regulates the somatic embryogenesis process. Especially, microRNAs (miRNAs) have emerged… read more here.
Keywords: signaling pathways; embryogenesis; key regulators; somatic embryogenesis ... See more keywords
Effect of key regulators in augmenting transcriptional expression of Transglutaminase in Streptomyces mobaraensis.
Sign Up to like & getrecommendations! Published in 2021 at "Bioresource technology"
DOI: 10.1016/j.biortech.2021.125627
Abstract: Transglutaminase forms isopeptide bonds in proteins which are helpful in various industrial applications. However, low productivity and high cost are the major bottlenecks for industrial Transglutaminase production. The present study describes the regulatory mechanism of… read more here.
Keywords: production; transglutaminase; key regulators; effect key ... See more keywords
Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca2+-ATPases and Key Regulators of Ca2+ Clearance
Sign Up to like & getrecommendations! Published in 2017 at "Neuron"
DOI: 10.1016/j.neuron.2017.09.038
Abstract: Plasma membrane Ca2+-ATPases (PMCAs), a family of P-type ATPases, extrude Ca2+ ions from the cytosol to the extracellular space and are considered to be key regulators of Ca2+ signaling. Here we show by functional proteomics… read more here.
Keywords: key regulators; neuroplastin basigin; ca2; membrane ca2 ... See more keywords
The landscape of multiscale transcriptomic networks and key regulators in Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-13144-y
Abstract: Genetic and genomic studies have advanced our knowledge of inherited Parkinson’s disease (PD), however, the etiology and pathophysiology of idiopathic PD remain unclear. Herein, we perform a meta-analysis of 8 PD postmortem brain transcriptome studies… read more here.
Keywords: landscape multiscale; transcriptomic networks; analysis; key regulators ... See more keywords
Identification of key regulators in prostate cancer from gene expression datasets of patients
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-52896-x
Abstract: Identification of key regulators and regulatory pathways is an important step in the discovery of genes involved in cancer. Here, we propose a method to identify key regulators in prostate cancer (PCa) from a network… read more here.
Keywords: network; identification key; key regulators; prostate cancer ... See more keywords
Computational modeling to determine key regulators of hypoxia effects on the lactate production in the glycolysis pathway
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-66059-w
Abstract: In solid tumors, hypoxia can trigger aberrant expression of transcription factors and genes, resulting in abnormal biological functions such as altered energetic pathways in cancer cells. Glucose metabolism is an important part of this phenomenon,… read more here.
Keywords: determine key; glycolysis; glycolysis pathway; key regulators ... See more keywords
Transcriptomic analysis of equine placenta reveals key regulators and pathways involved in ascending placentitis†
Sign Up to like & getrecommendations! Published in 2020 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioaa209
Abstract: Abstract Improved understanding of the molecular mechanisms underlying ascending equine placentitis holds the potential for the development of new diagnostic tools and therapies to forestall placentitis-induced preterm labor. The current study characterized the equine placental… read more here.
Keywords: analysis; key regulators; equine placenta; regulators pathways ... See more keywords
R-loops: emerging key regulators in plants.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of experimental botany"
DOI: 10.1093/jxb/erac433
Abstract: The biological implications of R-loops are increasingly receiving attention in plant biology. Compared with recent progresses in humans, the studies of R-loops in plants are lagging behind. Massive efforts must be invested by the plant… read more here.
Keywords: regulators plants; biology; emerging key; plant ... See more keywords
Short chain fatty acids: key regulators of the local and systemic immune response in inflammatory diseases and infections
Sign Up to like & getrecommendations! Published in 2023 at "Open Biology"
DOI: 10.1098/rsob.230014
Abstract: The human intestinal microbiome substantially affects human health and resistance to infections in its dynamic composition and varying release of microbial-derived metabolites. Short-chain fatty acids (SCFA) produced by commensal bacteria through fermentation of indigestible fibres… read more here.
Keywords: chain fatty; immune response; fatty acids; response ... See more keywords
Reactive oxygen species: key regulators in vascular health and diseases
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Pharmacology"
DOI: 10.1111/bph.13828
Abstract: ROS are a group of small reactive molecules that play critical roles in the regulation of various cell functions and biological processes. In the vascular system, physiological levels of ROS are essential for normal vascular… read more here.
Keywords: reactive oxygen; oxygen species; key regulators; species key ... See more keywords