Dysregulation of NEUROG2 plays a key role in focal cortical dysplasia
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Neurology"
DOI: 10.1002/ana.25187
Abstract: Focal cortical dysplasias (FCDs) are an important cause of drug‐resistant epilepsy. In this work, we aimed to investigate whether abnormal gene regulation, mediated by microRNA, could be involved in FCD type II. read more here.
Keywords: role focal; focal cortical; neurog2 plays; dysregulation neurog2 ... See more keywords
The key role of organic anion transporter 3 in the drug-drug interaction between tranilast and methotrexate.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.22983
Abstract: Tranilast, N-(3',4'-dimethoxycinnamoyl)-anthranilic acid, is an anti-allergic drug and is considered for use in the treatment of rheumatoid arthritis. Methotrexate, an antimetabolite and folate antagonist to treat some cancers, is also a first-line drug for RA.… read more here.
Keywords: mtx; drug drug; drug; methotrexate ... See more keywords
Saving lives, one breath at a time: The key role of noninvasive ventilation interfaces
Sign Up to like & getrecommendations! Published in 2024 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.27306
Abstract: Home noninvasive ventilation (NIV) for children must consider the key role of the interface, in addition to selecting the ventilatory mode and settings. Acceptance and adherence to NIV often depend on the time spent selecting… read more here.
Keywords: saving lives; time; noninvasive ventilation; key role ... See more keywords
Guidelines Have a Key Role in Driving HCV Elimination by Advocating for Simple HCV Care Pathways
Sign Up to like & getrecommendations! Published in 2021 at "Advances in Therapy"
DOI: 10.1007/s12325-021-01636-7
Abstract: The availability of pangenotypic direct-acting antivirals for treatment of hepatitis C (HCV) has provided an opportunity to simplify patient pathways. Recent clinical practice guidelines have recognised the need for simplification to ensure that elimination of… read more here.
Keywords: guidelines key; hcv; driving hcv; role driving ... See more keywords
The Emerging Key Role of Klotho in the Hypothalamus–Pituitary–Ovarian Axis
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive Sciences"
DOI: 10.1007/s43032-020-00277-5
Abstract: The hypothalamus–pituitary–ovary axis is the most important system for regulating female reproductive endocrine function. Its dysfunction would lead to the abnormal secretion of gonadotropin-releasing hormone, follicle-stimulating hormone, or luteinizing hormone, and eventually result in the… read more here.
Keywords: axis; hypothalamus pituitary; klotho; key role ... See more keywords
Key role of different levels of dissolved oxygen in hydrolyzed polyacrylamide bioconversion: Focusing on metabolic products, key enzymes and functional microorganisms.
Sign Up to like & getrecommendations! Published in 2020 at "Bioresource technology"
DOI: 10.1016/j.biortech.2020.123089
Abstract: Dissolved oxygen (DO) played a short board effect on nitrogen biotransformation and pollutant metabolism. This study for the first time explored the key role of different levels of DO (covering anaerobic, anoxic and aerobic) on… read more here.
Keywords: bioconversion; hydrolyzed polyacrylamide; different levels; role different ... See more keywords
Comprehensive Immunoprofiling of Pediatric Zika Reveals Key Role for Monocytes in the Acute Phase and No Effect of Prior Dengue Virus Infection.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.107569
Abstract: Zika virus (ZIKV) is an emerging, mosquito-borne flavivirus responsible for recent epidemics across the Americas, and it is closely related to dengue virus (DENV). Here, we study samples from 46 DENV-naive and 43 DENV-immune patients… read more here.
Keywords: dengue virus; zikv infection; infection; key role ... See more keywords
Key role of network formation in Rutting, fatigue and brittle performance of bitumen/PEG/MDI/SiO2 composites
Sign Up to like & getrecommendations! Published in 2021 at "Construction and Building Materials"
DOI: 10.1016/j.conbuildmat.2021.123739
Abstract: Abstract The effect of hydrophilic SiO2 content on the rheological property of bitumen (B)/ polyethylene glycol (PEG)/4,4′-diphenylmethane diisocyanate (MDI)/SiO2 composite was investigated. The multiple stress creep and recovery (MSCR) and linear amplitude sweep (LAS) tests… read more here.
Keywords: key role; mdi sio2; performance; peg mdi ... See more keywords
Identification of a miRNAs signature associated with exposure to stress early in life and enhanced vulnerability for schizophrenia: New insights for the key role of miR-125b-1-3p in neurodevelopmental processes
Sign Up to like & getrecommendations! Published in 2019 at "Schizophrenia Research"
DOI: 10.1016/j.schres.2018.07.030
Abstract: Epidemiological and clinical studies have provided evidence for a role of both genetic and environmental factors, such as stressful experiences early in life, in the pathogenesis of Schizophrenia (SZ) and microRNAs (miRNAs) have been suggested… read more here.
Keywords: mir 125b; stress; early life; key role ... See more keywords
Key Role of Vegetation Cover in Alleviating Microplastic-Enhanced Carbon Emissions.
Sign Up to like & getrecommendations! Published in 2024 at "Environmental science & technology"
DOI: 10.1021/acs.est.3c10017
Abstract: Microplastics (MPs) are considered to influence fundamental biogeochemical processes, but the effects of plant residue-MP interactions on soil carbon turnover in urban greenspaces are virtually unknown. Here, an 84-day incubation experiment was constructed using four… read more here.
Keywords: carbon; plant; key role; vegetation ... See more keywords
Key Role of Defects in Thermoelectric Performance of TiMSn (M = Ni, Pd, and Pt) Half-Heusler Alloys
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Physical Chemistry C"
DOI: 10.1021/acs.jpcc.0c03243
Abstract: Half-Heusler alloys are thermoelectric materials that enable direct conversion of waste heat to electricity. A systematic study of these alloys has never been attempted using local Gaussian type or... read more here.
Keywords: heusler alloys; role defects; key role; half heusler ... See more keywords