Monitoring of dynamic changes in Keyhole Limpet Hemocyanin (KLH)-specific B cells in KLH-vaccinated cancer patients
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep43486
Abstract: Keyhole limpet hemocyanin (KLH) is used as an immunogenic neo-antigen for various clinical applications and during vaccine development. For advanced monitoring of KLH-based interventions, we developed a flow cytometry-based assay for the ex vivo detection,… read more here.
Keywords: klh; limpet hemocyanin; keyhole limpet; hemocyanin klh ... See more keywords
A randomized controlled trial with a delayed‐type hypersensitivity model using keyhole limpet haemocyanin to evaluate adaptive immune responses in man
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DOI: 10.1111/bcp.14588
Abstract: Keyhole limpet haemocyanin (KLH) immunization is a clinical model for the evaluation of human antibody responses. The current study evaluated the anti‐KLH antibody response after KLH immunization and the delayed‐type hypersensitivity response following intradermal KLH… read more here.
Keywords: keyhole limpet; type hypersensitivity; limpet haemocyanin; delayed type ... See more keywords
Safety and Toxicological Evaluation of Subunit Keyhole Limpet Hemocyanin-Loaded Lipid–PLGA Hybrid Nanoparticles (sKLH-hNPs) as a Nanocarrier for an Opioid Use Disorder Vaccine
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DOI: 10.1177/10915818251355948
Abstract: A nanoparticle-based immunization strategy offers a promising treatment for opioid use disorder (OUD). This study tested the in vivo safety of subunit keyhole limpet hemocyanin-loaded lipid–PLGA hybrid nanoparticles (sKLH-hNPs) as a nanocarrier for OUD vaccine… read more here.
Keywords: subunit keyhole; use disorder; opioid use; limpet hemocyanin ... See more keywords
Genetic Insights into the Giant Keyhole Limpet (Megathura crenulata), an Eastern Pacific Coastal Endemic: Complete Mitogenome, Phylogenetics, Phylogeography, and Historical Demography
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DOI: 10.3390/genes15101303
Abstract: Background: The giant keyhole limpet Megathura crenulata is a gastropod mollusk (Fissurella superfamily) that is endemic to the eastern Pacific coast from southern California, USA, to Baja California Sur, Mexico. M. crenulata is socioeconomically important… read more here.
Keywords: giant keyhole; demography; crenulata; phylogenetics ... See more keywords