Transfer of miR‐4755‐5p through extracellular vesicles and particles induces decitabine resistance in recipient cells by targeting CDKN2B
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23521
Abstract: Decitabine (5‐aza‐2‐deoxycytidine, DAC), a DNA‐hypomethylating agent, has been one of the frontline therapies for clonal hematopoietic stem cell disorders, such as myelodysplastic syndrome and acute myeloid leukemia, but DAC‐resistance often occurs and leads to treatment… read more here.
Keywords: extracellular vesicles; mir 4755; resistance; dac ... See more keywords
Evidence for Hesperidin as an Effective Factor in Initiating the Intrinsic Pathway of Apoptosis in KG1a Leukemia Cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Toxicology"
DOI: 10.1177/10915818221146468
Abstract: Acute myeloid leukemia (AML) is the most common subtype of leukemia, accounting for 62% of all leukemia fatalities. As a polyphenol glycoside, hesperidin triggers the apoptotic pathway, which might positively affect combating cancer cells. In… read more here.
Keywords: cell; effective factor; factor initiating; leukemia ... See more keywords