Berberine attenuates arthritis in adjuvant‐induced arthritic rats associated with regulating polarization of macrophages through AMPK/NF‐&kgr;B pathway
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2019.02.036
Abstract: ABSTRACT Berberine (BBR) is a traditional folk medicine with excellent anti‐inflammatory properties. This study aimed to investigate the anti‐arthritic effects of BBR in adjuvant arthritis (AA) in rats and its regulatory role in the polarization… read more here.
Keywords: kgr pathway; polarization macrophages; regulating polarization; macrophages ampk ... See more keywords
Plasma‐derived exosomes contribute to inflammation via the TLR9‐NF‐&kgr;B pathway in chronic heart failure patients
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Immunology"
DOI: 10.1016/j.molimm.2017.03.011
Abstract: HighlightsPlasma‐derived exosomes carried mtDNA.Exosomes contribute to inflammation through the mtDNA‐TLR9‐NF‐&kgr;B pathway.Chloroquine can block this pathway. Abstract Exosomes are small vesicles that contain proteins, DNA and RNA, and play an important role in inflammation; however, the… read more here.
Keywords: kgr pathway; inflammation; tlr9 kgr; plasma derived ... See more keywords