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   Articles with "kgr signaling" as a keyword



Akt1/NF&kgr;B signaling pathway activation by a small molecule DMA confers radioprotection to intestinal epithelium in xenograft model

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recommendations! Published in 2017 at "Free Radical Biology and Medicine"

DOI: 10.1016/j.freeradbiomed.2017.04.029

Abstract: Abstract Normal tissue protection and recovery of radiation‐induced damage are of paramount importance for development of radioprotector. Radioprotector which selectively protects normal tissues over cancerous tissues improves the therapeutic window of radiation therapy. In the… read more here.

Keywords: dma; kgr signaling; akt1 kgr; molecule dma ... See more keywords

Luteoloside attenuates neuroinflammation in focal cerebral ischemia in rats via regulation of the PPAR&ggr;/Nrf2/NF‐&kgr;B signaling pathway

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recommendations! Published in 2019 at "International Immunopharmacology"

DOI: 10.1016/j.intimp.2018.11.044

Abstract: &NA; Luteoloside, a flavonoid compound, has been reported to have anti‐inflammatory, anti‐oxidative, antibacterial, antiviral, anticancer, and cardioprotective effects, among others, but its neuroprotective effects have rarely been studied. The purpose of this study was to… read more here.

Keywords: kgr signaling; cerebral ischemia; focal cerebral; ppar ggr ... See more keywords
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p55PIK regulates alpha‐fetoprotein expression through the NF‐&kgr;B signaling pathway

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recommendations! Published in 2017 at "Life Sciences"

DOI: 10.1016/j.lfs.2017.09.043

Abstract: Aims: Alpha‐fetoprotein (AFP) is regarded as a diagnostic and prognostic biomarker and a potential therapeutic target for hepatocellular carcinoma (HCC). However, the regulation of AFP expression in HCC remains poorly understood. This study aimed to… read more here.

Keywords: kgr signaling; signaling pathway; expression; afp expression ... See more keywords

Cordycepin mitigates MPTP‐induced Parkinson's disease through inhibiting TLR/NF‐&kgr;B signaling pathway

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recommendations! Published in 2019 at "Life Sciences"

DOI: 10.1016/j.lfs.2019.02.037

Abstract: Abstract Parkinson's disease (PD) is a neurodegenerative disease with movement disorder. PD is characterized by the loss of dopaminergic (DA) neurons in the substantia nigra. Cordycepin, a small molecule extracted from cordyceps sinensis, has neuroprotective,… read more here.

Keywords: kgr signaling; tlr kgr; disease; signaling pathway ... See more keywords

Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF‐&kgr;B signaling pathway in a mouse model of Parkinson's disease

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recommendations! Published in 2019 at "Life Sciences"

DOI: 10.1016/j.lfs.2019.03.030

Abstract: Abstract Inflammation contributes to the pathological processes in patients and animal models of PD. Rosmarinic acid (RA) has been demonstrated to protect neurons in PD models. The present study aimed to evaluate the anti‐inflammatory effect… read more here.

Keywords: inflammatory responses; hmgb1 tlr4; rosmarinic acid; kgr signaling ... See more keywords